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Nature of Business and Plan of Operations (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Dec. 31, 2018
Dec. 31, 2017
Net loss     $ (108,947) $ (127,044)    
Accumulated deficit $ (1,292,282)   (1,292,282)   $ (1,183,335)  
Total revenues 13,281 $ 10,928 37,407 40,030    
Cash and cash equivalents $ 204,491 $ 303,205 $ 204,491 $ 303,205 $ 262,252 $ 267,107
Number of months Capital resources meets capital expenditures     12 months      
Product            
Total revenues     $ 0