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Summary of Significant Accounting Policies - Segments (Details) - item
3 Months Ended 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Jun. 30, 2019
Jun. 30, 2018
Segment Information        
Number of operating segments     1  
Other customers        
Segment Information        
Percentages of revenue recognized 0.00% 0.00% 0.00% 0.00%
Novartis        
Segment Information        
Percentages of revenue recognized   11.00%   4.00%
Roche        
Segment Information        
Percentages of revenue recognized 99.00% 78.00% 99.00% 50.00%
Takeda        
Segment Information        
Percentages of revenue recognized   1.00%   39.00%