CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
ASSETS
Cash and cash equivalents	$ 239,825	$ 262,252
Accounts receivable		1,701
Unbilled revenue/reimbursement	2,474	617
Contract asset	0	500
Non-cash royalty receivable	10,430	9,249
Prepaid and other current assets	6,649	4,462
Total current assets	259,378	278,781
Property and equipment, net of accumulated depreciation	10,052	12,891
Operating lease right-of-use assets	16,389
Other assets	1,850	3,709
Total assets	287,669	295,381
LIABILITIES AND SHAREHOLDERS (DEFICIT) EQUITY
Accounts payable	7,809	11,365
Accrued compensation	19,564	11,796
Other accrued liabilities	14,681	20,465
Current portion of deferred lease incentive		837
Current portion of liability related to the sale of future royalties, net of deferred financing costs of $715 and $753, respectively	29,484	25,880
Current portion of operating lease liability	2,761
Current portion of deferred revenue	317	317
Total current liabilities	74,616	70,660
Deferred lease incentive, net of current portion		4,675
Deferred revenue, net of current portion	145,614	80,485
Operating lease liability - net of current portion	23,334
Convertible 4.5% senior notes, net of deferred financing costs of $29 and $36, respectively	2,071	2,064
Liability related to the sale of future royalties, net of current portion and deferred financing costs of $1,175 and $1,536, respectively	108,265	122,345
Other long-term liabilities	1,943	4,180
Total liabilities	355,843	284,409
Commitments and contingencies (Note I)
Shareholders' deficit:
Preferred stock, $.01 par value; authorized 5,000 shares; no shares issued and outstanding
Common stock, $0.01 par value; authorized 200,000 shares; issued and outstanding 149,885 and 149,400 shares as of June 30, 2019 and December 31, 2018, respectively	1,498	1,494
Additional paid-in capital	1,200,860	1,192,813
Accumulated deficit	(1,270,532)	(1,183,335)
Total shareholders (deficit) equity	(68,174)	10,972
Total liabilities and shareholders (deficit) equity	$ 287,669	$ 295,381