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- Definition

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+ References

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- Definition

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+ References

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No definition available.

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Amount, before allowance for credit loss, of right to consideration in exchange for good or service transferred to customer, when right is conditioned on something other than passage of time.

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The aggregate costs related to goods produced and sold and services rendered by an entity during the reporting period. This excludes costs incurred during the reporting period related to financial services rendered and other revenue generating activities.

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Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise.

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Agreements - Novartis (Details)	1 Months Ended			3 Months Ended														6 Months Ended		12 Months Ended
Agreements - Novartis (Details)	Oct. 31, 2014 USD ($) item	Oct. 31, 2013 USD ($)	Mar. 31, 2013 USD ($) item	Dec. 31, 2018 USD ($)	Sep. 30, 2018 USD ($)	Jun. 30, 2018 USD ($)	Mar. 31, 2018 USD ($)	Dec. 31, 2017 USD ($)	Sep. 30, 2017 USD ($)	Jun. 30, 2017 USD ($)	Mar. 31, 2017 USD ($)	Dec. 31, 2016 USD ($)	Sep. 30, 2016 USD ($)	Jun. 30, 2016 USD ($)	Mar. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)	Sep. 30, 2015 USD ($)	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)	Dec. 31, 2018 USD ($) item	Dec. 31, 2017 USD ($)	Dec. 31, 2016 USD ($)	Jun. 30, 2016 USD ($)	Dec. 31, 2010 USD ($) item	May 31, 2015 USD ($)	Jan. 31, 2015 USD ($)
Collaborative Agreements disclosures
Revenue from contract with customer				$ 13,416,000	$ 10,928,000	$ 9,287,000	$ 19,815,000	$ 39,448,000	$ 8,480,000	$ 39,020,000	$ 28,499,000	$ 13,846,000	$ 7,660,000	$ 7,408,000	$ 19,714,000	$ 18,029,000	$ 14,851,000	$ 21,506,000	$ 32,880,000	$ 53,446,000	$ 115,447,000	$ 48,628,000	$ 60,002,000
Novartis
Collaborative Agreements disclosures
Number of single-target licenses \| item			1																	5				6
Term of agreement		1 year																						3 years
Number of related targets \| item			2
Number of remaining licenses \| item	3
Novartis \| Right-to-test agreement
Collaborative Agreements disclosures
Revenue from contract with customer		$ 5,000,000
Novartis \| License amendments
Collaborative Agreements disclosures
Revenue from contract with customer			$ 3,500,000
Novartis \| Development milestones
Collaborative Agreements disclosures
Potential milestone payment																								$ 22,500,000	$ 5,000,000	$ 5,000,000
Novartis \| Phase 1 clinical trial
Collaborative Agreements disclosures
Revenue from contract with customer																					5,000,000
Potential milestone payment				5,000,000																$ 5,000,000
Novartis \| Phase 2 clinical trial
Collaborative Agreements disclosures
Potential milestone payment				7,500,000																7,500,000
Novartis \| Regulatory milestones
Collaborative Agreements disclosures
Potential milestone payment																								77,000,000
Novartis \| Milestone payments
Collaborative Agreements disclosures
Potential milestone payment	$ 199,500,000																							100,000,000
Upfront payment \| Novartis
Collaborative Agreements disclosures
Revenue from contract with customer	$ 1,000,000		$ 1,000,000																					45,000,000
License and milestone fees
Collaborative Agreements disclosures
Revenue from contract with customer				1,747,000	672,000	1,321,000	11,540,000	29,580,000	79,000	31,080,000	18,730,000	5,076,000	76,000	76,000	10,077,000	10,692,000	6,070,000	5,152,000	16,762,000	15,280,000	79,469,000	15,305,000	26,915,000
License and milestone fees \| Novartis
Collaborative Agreements disclosures
Revenue from contract with customer																				978,000
Potential milestone payment																								199,500,000
Exercise fee \| Novartis
Collaborative Agreements disclosures
Revenue from contract with customer																								$ 1,000,000
Research and development support
Collaborative Agreements disclosures
Revenue from contract with customer				$ 218,000	$ 388,000	$ 388,000	$ 383,000	$ 452,000	$ 650,000	$ 902,000	$ 1,478,000	$ 1,427,000	$ 1,354,000	$ 1,335,000	$ 1,059,000	$ 848,000	$ 772,000	2,781,000	$ 1,620,000	1,377,000	3,482,000	$ 5,175,000	4,014,000
Costs of services and materials																		22,000
Research and development support \| Novartis
Collaborative Agreements disclosures
Costs of services and materials																		$ 17,000		$ 0	$ 32,000		$ 67,000