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Nature of Business and Plan of Operations (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Net loss     $ (127,044) $ (82,894)    
Accumulated deficit $ (1,141,536)   (1,141,536)   $ (1,028,582)  
Revenue 10,928 $ 8,480 40,030 75,999    
Cash and cash equivalents $ 303,205 $ 194,851 $ 303,205 $ 194,851 $ 267,107 $ 159,964
Number of months Capital resources meets capital expenditures     12 months      
Product            
Revenue     $ 0