Agreements - Jazz (Details) - Jazz $ in Millions	1 Months Ended	3 Months Ended	9 Months Ended
	Aug. 31, 2017 USD ($) product item	Sep. 30, 2017 USD ($)	Sep. 30, 2017 USD ($)
Collaborative Agreements disclosures
Number of early stage ADC programs | item	2
Number of ADC programs | item	3
Payments received under collaboration agreement	$ 75.0
Potential milestone payments	$ 100.0
Term of agreement	7 years
Number of products with rights to co-commercialize | product	1
Number of products with rights under certain limited circumstances | product	2
Offset to research and development expense		$ 1.3	$ 1.3
Number of development and commercialization licenses | item	3
Discount rate (as a percent)	14.00%
Estimated utilization period after commercialization	10 years
Remaining arrangement consideration to be recognized as license revenue		$ 75.0	$ 75.0