CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2017	Dec. 31, 2016
ASSETS
Cash and cash equivalents	$ 194,851	$ 159,964
Accounts receivable	2,521	2,026
Unbilled revenue	2,600	6,778
Inventory	2,243	2,192
Prepaid and other current assets	4,745	5,386
Total current assets	206,960	176,346
Property and equipment, net of accumulated depreciation	15,622	19,498
Other assets	3,113	3,020
Total assets	225,695	198,864
LIABILITIES AND SHAREHOLDERS' DEFICIT
Accounts payable	6,614	7,895
Accrued compensation	8,525	6,946
Other accrued liabilities	13,956	11,150
Current portion of deferred lease incentive	784	784
Current portion of liability related to the sale of future royalties, net of deferred financing costs of $792 and $850, respectively	16,703	14,470
Current portion of deferred revenue	27,073	14,531
Total current liabilities	73,655	55,776
Deferred lease incentive, net of current portion	5,325	5,914
Deferred revenue, net of current portion	93,832	19,086
Convertible 4.5% senior notes, net of deferred financing costs of $78 and $3,035, respectively	3,022	96,965
Liability related to the sale of future royalties, net of current portion and deferred financing costs of $2,559 and $3,144, respectively	157,080	169,858
Other long-term liabilities	4,076	4,115
Total liabilities	336,990	351,714
Commitments and contingencies (Note H)
Shareholders' deficit:
Preferred stock, $0.01 par value; authorized 5,000 shares; no shares issued and outstanding
Common stock, $0.01 par value; authorized 200,000 shares; issued and outstanding 115,563 and 87,301 shares as of September 30, 2017 and December 31, 2016, respectively	1,156	873
Additional paid-in capital	903,013	778,847
Accumulated deficit	(1,015,464)	(932,570)
Total shareholders’ deficit	(111,295)	(152,850)
Total liabilities and shareholders’ deficit	$ 225,695	$ 198,864