CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2017	Dec. 31, 2016
ASSETS
Cash and cash equivalents	$ 126,568	$ 159,964
Accounts receivable	3,893	2,026
Unbilled revenue	2,051	6,778
Inventory	3,225	2,192
Prepaid and other current assets	6,394	5,386
Total current assets	142,131	176,346
Property and equipment, net of accumulated depreciation	17,997	19,498
Other assets	3,193	3,020
Total assets	163,321	198,864
LIABILITIES AND SHAREHOLDERS' DEFICIT
Accounts payable	5,100	7,895
Accrued compensation	4,927	6,946
Other accrued liabilities	12,078	11,150
Current portion of deferred lease incentive	784	784
Current portion of liability related to the sale of future royalties, net of deferred financing costs of $xxx and $850, respectively	15,664	14,470
Current portion of deferred revenue	1,814	14,531
Total current liabilities	40,367	55,776
Deferred lease incentive, net of current portion	5,718	5,914
Deferred revenue, net of current portion	18,992	19,086
Convertible 4.5% senior notes, net of deferred financing costs of $2,869 and $3,035, respectively	97,131	96,965
Liability related to the sale of future royalties, net of current portion and deferred financing costs of $2,943 and $3,144, respectively	164,460	169,858
Other long-term liabilities	4,183	4,115
Total liabilities	330,851	351,714
Commitments and contingencies (Note H)
Shareholders' deficit:
Preferred stock, $0.01 par value; authorized 5,000 shares; no shares issued and outstanding
Common stock, $0.01 par value; authorized 150,000 shares; issued and outstanding 89,348 and 87,301 shares as of March 31, 2017 and December 31, 2016, respectively	893	873
Additional paid-in capital	781,492	778,847
Accumulated deficit	(949,915)	(932,570)
Total shareholders’ deficit	(167,530)	(152,850)
Total liabilities and shareholders’ deficit	$ 163,321	$ 198,864