Agreements - Janssen (Details) - USD ($)	1 Months Ended	3 Months Ended										6 Months Ended		12 Months Ended
	Dec. 31, 2004	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2015	Sep. 30, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2014	Sep. 30, 2014	Dec. 31, 2016	Dec. 31, 2015	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2014
Collaborative Agreements disclosures
License and milestone fees		$ 5,076,000	$ 76,000	$ 76,000	$ 10,077,000	$ 10,692,000	$ 6,070,000	$ 5,086,000	$ 5,078,000	$ 41,417,000	$ 6,234,000	$ 5,152,000	$ 16,762,000	$ 26,915,000	$ 57,815,000	$ 39,455,000
Janssen
Collaborative Agreements disclosures
License and milestone fees															$ 241,000
Payments received under collaboration agreement	$ 1,000,000