Represents the opt-in-fee payable by the entity upon exercise of rights under the collaborative arrangement.

No definition available.

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- Definition

Represents the amount of potential payments that could be received under the collaborative agreement.

+ References

No definition available.

+ Details

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

Total costs related to goods produced and sold during the reporting period.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.2(a))
-URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688

+ Details

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- Definition

Cash received from collaborators during the current period.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 25
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3536-108585

+ Details

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- Definition

The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 730
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 985
-SubTopic 20
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756

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- Details

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- Details

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- Details

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Agreements - Biotest (Details) - USD ($)	1 Months Ended	3 Months Ended										6 Months Ended		12 Months Ended
Agreements - Biotest (Details) - USD ($)	Sep. 30, 2008	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2015	Sep. 30, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2014	Sep. 30, 2014	Dec. 31, 2016	Dec. 31, 2015	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2014	Dec. 31, 2006
Collaborative Agreements disclosures
Costs related to the research and development services		$ 33,657,000	$ 32,909,000	$ 38,652,000	$ 36,094,000	$ 38,199,000	$ 35,132,000	$ 30,437,000	$ 25,666,000	$ 27,647,000	$ 28,018,000	$ 66,566,000	$ 73,331,000	$ 148,077,000	$ 111,768,000	$ 106,958,000
Biotest
Collaborative Agreements disclosures
Payments received under collaboration agreement																	$ 1,000,000
Potential milestone payments																	35,500,000
Opt-in-fee payable on exercise of right																	15,000,000
Costs related to the research and development services												22,000		160,000	309,000	305,000
Costs related to clinical materials sold												549,000		$ 1,800,000	$ 3,000,000	$ 670,000
Biotest \| Development milestones
Collaborative Agreements disclosures
Payments received under collaboration agreement	$ 500,000
Potential milestone payments																	4,500,000
Biotest \| Phase IIb Clinical Trial
Collaborative Agreements disclosures
Potential milestone payments		$ 2,000,000										$ 2,000,000
Biotest \| Regulatory milestones
Collaborative Agreements disclosures
Potential milestone payments																	$ 31,000,000