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Liability Related to Sale of Future Royalties (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 18 Months Ended
Apr. 30, 2015
Sep. 30, 2016
Sep. 30, 2015
Sep. 30, 2016
Roll forward        
Non-cash Kadcyla royalty revenue   $ (6,184) $ (5,684)  
Non-cash interest expense recognized   5,018 $ 5,143  
Kadcyla        
Liability Related to Sale of Future Royalties        
Percentage of royalty payments if applicable threshold is met 85.00%      
Kadcyla | IRH        
Liability Related to Sale of Future Royalties        
Percentage of royalty payments 100.00%      
Royalty revenue $ 235,000     $ 37,000
Royalties on net sales of Kadcyla when royalties to the purchaser reach a specified milestone $ 260,000      
Percentage of royalty payments if applicable threshold is met 15.00%      
Proceeds from sale of future royalties $ 200,000      
Transaction costs for royalty agreements $ 5,900      
Roll forward        
Liability related to sale of future royalties, net — beginning balance   188,899    
Non-cash Kadcyla royalty revenue   (6,184)    
Non-cash interest expense recognized   4,847    
Liability related to sale of future royalties, net — ending balance   $ 187,562   $ 187,562
Effective annual interest rate   9.60%