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Income Taxes - Expense (Details) - USD ($)
$ in Thousands
12 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2014
Reconciliation of the expected statutory tax benefit to the actual income taxes      
U.S. federal corporate tax rate (as a percent) 34.00% 34.00% 34.00%
Loss before income tax expense $ (144,817) $ (60,739) $ (71,364)
Expected tax benefit at 34% (49,238) (20,651) (24,264)
Permanent differences 345 818 215
Incentive stock options 2,501 1,948 1,738
State tax benefit net of federal benefit (7,954) (3,252) (4,062)
Increase in valuation allowance, net 62,505 27,940 26,011
Federal research credit (4,109) (1,407) (1,002)
Federal orphan drug credit (4,241) (5,471)  
Expired loss and credit carryforwards 184 $ 75 $ 1,364
Other $ 7