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Liability Related to Sale of Future Royalties (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended 15 Months Ended
Apr. 30, 2015
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2014
Jun. 30, 2016
Liability Related to Sale of Future Royalties                          
Royalty revenue       $ 195   $ (23) $ 5,099 $ 4,625 $ 4,166 $ 195 $ 13,867 $ 10,346  
Transaction costs for royalty agreements                   5,865      
Movement in Deferred Revenue [Roll Forward]                          
Proceeds from sale of future royalties                     194,135    
Non-cash Kadcyla royalty revenue   $ (5,944) $ (7,380) (6,291) $ (5,684) (5,484)       (25,299) (5,484)    
Non-cash interest expense on liability related to sale of future royalties and convertible senior notes   4,956 $ 4,972 $ 5,059 5,143 5,437       20,130 5,437    
Kadcyla                          
Liability Related to Sale of Future Royalties                          
Percentage of royalty payments if applicable threshold is met 85.00%                        
Kadcyla | IRH                          
Liability Related to Sale of Future Royalties                          
Percentage of royalty payments 100.00%                        
Royalty revenue $ 235,000                        
Royalties on net sales of Kadcyla when royalties to the purchaser reach a specified milestone $ 260,000                        
Percentage of royalty payments if applicable threshold is met 15.00%                        
Transaction costs for royalty agreements $ 5,900                        
Movement in Deferred Revenue [Roll Forward]                          
Liability related to sale of future royalties — beginning balance         $ 199,662         199,662      
Proceeds from sale of future royalties                         $ 200,000
Non-cash Kadcyla royalty revenue                   (25,299)     (30,783)
Non-cash interest expense on liability related to sale of future royalties and convertible senior notes                   19,009     24,155
Liability related to sale of future royalties — ending balance   $ 193,372       $ 199,662       $ 193,372 $ 199,662   $ 193,372
Effective annual interest rate                         9.60%