Agreements - Bayer (Details) - USD ($) $ in Thousands	1 Months Ended	3 Months Ended								12 Months Ended				102 Months Ended
	Jan. 31, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2015	Sep. 30, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2014	Sep. 30, 2014	Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2014	Dec. 31, 2008	Jun. 30, 2016	Dec. 31, 2006
Collaborative Agreements disclosures
Amount of arrangement consideration included in license and milestone fees		$ 76	$ 10,077	$ 10,692	$ 6,070	$ 5,086	$ 5,078	$ 41,417	$ 6,234	$ 26,915	$ 57,815	$ 39,455
Development and Commercialization License | Development milestones
Collaborative Agreements disclosures
Potential milestone payments															$ 4,500
Bayer | Development and Commercialization License
Collaborative Agreements disclosures
Payments received under collaboration agreement													$ 4,000	$ 13,000
Potential milestone payments													$ 170,500
Bayer | Development and Commercialization License | Minimum
Collaborative Agreements disclosures
Percentage of royalty payments													4.00%
Bayer | Development and Commercialization License | Maximum
Collaborative Agreements disclosures
Percentage of royalty payments													7.00%
Bayer | Development and Commercialization License | Development milestones
Collaborative Agreements disclosures
Potential milestone payments		6,000								6,000			$ 16,000	6,000
Bayer | Development and Commercialization License | Phase II clinical trial
Collaborative Agreements disclosures
Potential milestone payments		$ 2,000								$ 2,000				$ 2,000
Amount of arrangement consideration included in license and milestone fees	$ 10,000
Bayer | Development and Commercialization License | Regulatory milestones
Collaborative Agreements disclosures
Potential milestone payments													44,500
Bayer | Development and Commercialization License | Sales milestones
Collaborative Agreements disclosures
Potential milestone payments													$ 110,000