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Summary of Significant Accounting Policies (Details)
1 Months Ended 3 Months Ended
Oct. 31, 2015
USD ($)
Dec. 31, 2013
USD ($)
May. 31, 2013
USD ($)
item
Dec. 31, 2012
USD ($)
item
Dec. 31, 2011
item
Nov. 30, 2011
item
Nov. 30, 2009
USD ($)
item
Sep. 30, 2009
USD ($)
item
Sep. 30, 2015
USD ($)
item
Sep. 30, 2014
USD ($)
item
Jun. 30, 2015
USD ($)
Jun. 30, 2014
USD ($)
Summary of Significant Accounting Policies                        
Number of types of licensing and development agreements with collaborative partners                 2      
License and milestone fees | $                 $ 6,070,000 $ 6,234,000    
Financial Instruments and Concentration of Credit Risk                        
Number of financial institutions in the U.S. in which cash and cash equivalents are primarily maintained                 3      
Number of marketable securities held by entity | $                 $ 0   $ 0  
Cash and cash equivalents | $                 $ 247,843,000 121,798,000 $ 278,109,000 $ 142,261,000
Development and Commercialization License                        
Summary of Significant Accounting Policies                        
Average involvement period over which the upfront payments on single-target licenses are amortized                 6 years 6 months      
Difference between the full cost to manufacture and amounts received from collaborators for preclinical and clinical materials | $                 $ 7,000,000 3,100,000    
Number of types of milestone payments under collaborative arrangements                 3      
Number of quarters in arrear for revenue recognition                 1      
Development and Commercialization License | Minimum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 10 years      
Development and Commercialization License | Maximum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 12 years      
Development and Commercialization License | Kadcyla | Minimum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 10 years      
Development and Commercialization License | Kadcyla | Maximum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 12 years      
Right-to-test agreement | Minimum                        
Summary of Significant Accounting Policies                        
Average period over which upfront payments are deferred and recognized                 12 months      
Right-to-test agreement | Maximum                        
Summary of Significant Accounting Policies                        
Average period over which upfront payments are deferred and recognized                 18 months      
Amgen | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses           3     4      
License exercise fee | $       $ 1,000,000     $ 1,000,000 $ 1,000,000        
Amgen | Development and Commercialization License | Non-exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses     1                  
License exercise fee | $     $ 500,000                  
Amgen | Right-to-test agreement | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses       3     3 3        
Bayer HealthCare | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 1      
Biotest | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 1      
Lilly | Development and Commercialization License | Phase I clinical trial                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 2      
Lilly | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 3      
Lilly | Right-to-test agreement                        
Summary of Significant Accounting Policies                        
Number of single-target licenses         3              
Novartis | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 5      
Number of licenses to two related targets                 1      
Number of related targets                 2      
Roche | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 5      
Sanofi | Development and Commercialization License                        
Summary of Significant Accounting Policies                        
Number of related targets                 1      
License exercise fee | $   $ 2,000,000                    
License and milestone fees | $                   $ 1,700,000    
Sanofi | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 1      
Number of licenses to multiple individual targets                 1      
Oxford BioTherapeutics Ltd Member | Amgen | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                   1    
Subsequent event | Sanofi | Development and Commercialization License | Phase I clinical trial                        
Summary of Significant Accounting Policies                        
License and milestone fees | $ $ 2,000,000