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Agreements (Details 9)
1 Months Ended 3 Months Ended 12 Months Ended
Mar. 31, 2015
USD ($)
item
Jun. 30, 2015
USD ($)
Mar. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Sep. 30, 2014
USD ($)
Jun. 30, 2014
USD ($)
Mar. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Sep. 30, 2013
USD ($)
Jun. 30, 2015
USD ($)
Jun. 30, 2014
USD ($)
Jun. 30, 2013
USD ($)
Collaborative Agreements disclosures                        
Costs related to the research and development services   $ 30,437,000 $ 25,666,000 $ 27,647,000 $ 28,018,000 $ 25,787,000 $ 38,280,000 $ 20,862,000 $ 22,029,000 $ 111,768,000 $ 106,958,000 $ 87,073,000
Takeda                        
Collaborative Agreements disclosures                        
Payments received under collaboration agreement $ 31,400,000                      
Costs related to the research and development services                   $ 113,000    
Takeda | Future Technological Improvements                        
Collaborative Agreements disclosures                        
Payments received under collaboration agreement 2,100,000                      
Takeda | Research Services                        
Collaborative Agreements disclosures                        
Payments received under collaboration agreement $ 3,400,000                      
Takeda | Right-to-test agreement                        
Collaborative Agreements disclosures                        
Number of single-target licenses | item 2                      
Term of agreement 3 years                      
Term of extension of the agreement 1 year                      
Payments to be made for extension of agreement $ 4,000,000                      
Payments received under collaboration agreement 20,000,000                      
Takeda | Right-to-test agreement | Maximum                        
Collaborative Agreements disclosures                        
Potential milestone payments 210,000,000   210,000,000                  
Takeda | Right-to-test agreement | Development milestones | Maximum                        
Collaborative Agreements disclosures                        
Potential milestone payments 30,000,000   30,000,000                  
Takeda | Right-to-test agreement | Regulatory milestones | Maximum                        
Collaborative Agreements disclosures                        
Potential milestone payments 85,000,000   85,000,000                  
Takeda | Right-to-test agreement | Sales milestones | Maximum                        
Collaborative Agreements disclosures                        
Potential milestone payments 95,000,000   95,000,000                  
Takeda | Right-to-test agreement | Option To Expand Agreement                        
Collaborative Agreements disclosures                        
Payments to be made for extension of agreement 8,000,000                      
Takeda | Development and Commercialization License                        
Collaborative Agreements disclosures                        
Payments received under collaboration agreement $ 25,900,000                      
Discount rate (as a percent) 13.00%                      
Estimated utilization period after commercialization 10 years                      
Estimated term of development and commercialization license 25 years                      
Number of development and commercialization licenses | item 3                      
Takeda | Development and Commercialization License | Phase I clinical trial                        
Collaborative Agreements disclosures                        
Potential milestone payments $ 5,000,000   5,000,000                  
Takeda | Development and Commercialization License | Option To Expand Agreement                        
Collaborative Agreements disclosures                        
Value of collaborators licenses after extension $ 8,000,000   $ 8,000,000                  
Additional term of extension of the agreement 2 years                      
Number of development and commercialization licenses | item 2                      
Takeda | Development and Commercialization License | Option to expand agreement for one additional year                        
Collaborative Agreements disclosures                        
Term of extension of the agreement 1 year                      
Payments to be made for extension of agreement $ 4,000,000