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Agreements (Details 6) (USD $)
3 Months Ended 12 Months Ended 36 Months Ended 1 Months Ended 1 Months Ended 12 Months Ended 36 Months Ended 12 Months Ended 12 Months Ended
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2014
Novartis
Jun. 30, 2013
Novartis
Jun. 30, 2012
Novartis
Oct. 31, 2013
Novartis
Oct. 31, 2013
Novartis
Future Technological Improvements
Oct. 31, 2013
Novartis
Research Services
Nov. 30, 2013
Novartis
Right-to-test agreement
Oct. 31, 2013
Novartis
Right-to-test agreement
item
Mar. 31, 2013
Novartis
Right-to-test agreement
Oct. 31, 2010
Novartis
Right-to-test agreement
Jun. 30, 2014
Novartis
Right-to-test agreement
Mar. 31, 2013
Novartis
Right-to-test agreement
Undisclosed Target
item
Mar. 31, 2013
Novartis
Right-to-test agreement
Minimum
Undisclosed Target
Mar. 31, 2013
Novartis
Right-to-test agreement
Exclusive license
Undisclosed Target
item
Jun. 30, 2014
Novartis
Development and Commercialization License
Jun. 30, 2013
Novartis
Development and Commercialization License
Oct. 31, 2013
Novartis
Development and Commercialization License
Oct. 31, 2010
Novartis
Development and Commercialization License
Nov. 30, 2013
Novartis
Development and Commercialization License
Maximum
Oct. 31, 2013
Novartis
Development and Commercialization License
Maximum
Mar. 31, 2013
Novartis
Development and Commercialization License
Maximum
Oct. 31, 2010
Novartis
Development and Commercialization License
Maximum
Mar. 31, 2013
Novartis
Development and Commercialization License
Development milestones
Oct. 31, 2010
Novartis
Development and Commercialization License
Development milestones
Jun. 30, 2014
Novartis
Development and Commercialization License
Development milestones
Phase I clinical trial
item
Mar. 31, 2013
Novartis
Development and Commercialization License
Regulatory milestones
Oct. 31, 2010
Novartis
Development and Commercialization License
Regulatory milestones
Mar. 31, 2013
Novartis
Development and Commercialization License
Sales milestones
Oct. 31, 2010
Novartis
Development and Commercialization License
Sales milestones
Jun. 30, 2014
Novartis
Development and Commercialization License
Exclusive license
item
Collaborative Agreements disclosures                                                                                  
Term of agreement                                         3 years                                        
Term of extension of the agreement                                     1 year                                            
Payments for extension of agreement                                     $ 5,000,000                                            
Number of extension terms                                     1                                            
Additional term of extension of the agreement                                     1 year                                            
Payments received under collaboration agreement                             60,200,000 4,500,000 710,000 1,000,000 1,000,000 1,000,000 45,000,000             55,000,000                          
License exercise fee, per license                                                         1,000,000                        
Potential milestone payments receivable                                                           199,500,000 199,500,000 199,500,000 199,500,000 22,500,000 22,500,000 5,000,000 77,000,000 77,000,000 100,000,000 100,000,000  
Number of development and commercialization licenses taken                                                                       3         2
Number of pre-defined and related undisclosed targets                                             2   1                               2
License exercise fee, for the fourth license                                           1,000,000                                      
Agreed upon fee receivable on conversion of non-exclusive target to an exclusive target                                               5,000,000                                  
Payments received under collaboration agreement in connection with amended agreement                                       3,500,000                                          
Potential milestone payments under second option                                                               238,000,000   22,500,000     115,500,000   100,000,000    
Amount of arrangement consideration included in license and milestone fees 305,000 305,000 25,678,000 13,167,000 855,000 22,010,000 429,000 933,000 39,455,000 24,227,000 9,161,000                             17,200,000 11,100,000                            
Cumulative catch-up amount included in license and milestone fees                                                   1,000,000                              
Estimated utilization period after commercialization                                                   10 years                              
Discount rate (as a percent)                                                   16.00%                              
Estimated term of development and commercialization license                                                   25 years                              
Costs related to the research and development services 25,787,000 38,280,000 20,862,000 22,029,000 20,399,000 21,318,000 21,656,000 23,700,000 106,958,000 87,073,000 69,192,000 1,400,000 2,400,000 1,100,000                                                      
Costs related to clinical materials sold                       $ 1,300,000 $ 134,000 $ 14,000