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Agreements (Details 7) (Lilly, USD $)
12 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended
Jun. 30, 2012
Jun. 30, 2012
Sales milestones
Dec. 31, 2011
Right-to-test agreement
Jun. 30, 2012
Development and Commercialization License
Dec. 31, 2011
Development and Commercialization License
Dec. 31, 2011
Development and Commercialization License
Maximum
Jun. 30, 2012
Development and Commercialization License
Phase I clinical trial
Dec. 31, 2011
Development and Commercialization License
Development milestones
Dec. 31, 2011
Development and Commercialization License
Regulatory milestones
Dec. 31, 2011
Development and Commercialization License
Sales milestones
Jun. 30, 2012
Future Technological Improvements
Jun. 30, 2012
Research Services
Collaborative Agreements disclosures                        
Term of agreement     3 years                  
Payments received under collaboration agreement     $ 20,000,000                  
Potential milestone payments receivable for the first license under agreement           200,500,000 5,000,000 30,500,000 70,000,000 100,000,000    
License exercise fee, per subsequent license       2,000,000 2,000,000              
Potential milestone payments receivable for each subsequent license under agreement           199,000,000   29,000,000        
Allocation of fees to deliverables                        
Estimated utilization period after commercialization 10 years                      
Discount rate (as a percent) 16.00%                      
Total expected arrangement consideration $ 28,200,000 $ 800,000   $ 23,500,000             $ 600,000 $ 3,300,000
Estimated term of development and commercialization license       25 years