X0101 EFFECT 33 LIVE 2009-11-27 0001193125-09-241189 485APOS 0000851680 DOMINI SOCIAL INVESTMENT TRUST 033-29180 S000003423 Domini Social Equity Fund C000009466 Investor Shares S000003423 Domini Social Equity Fund C000009467 Class R Shares S000003423 Domini Social Equity Fund C000071455 Class A Shares S000003423 Domini Social Equity Fund C000071456 Institutional Shares S000003424 Domini Social Bond Fund C000009468 Investor Shares S000003425 Domini European Social Equity Fund C000009470 Investor Shares S000003425 Domini European Social Equity Fund C000071457 Class A Shares S000014393 Domini European PacAsia Social Equity Fund C000039201 Investor Shares S000014393 Domini European PacAsia Social Equity Fund C000071458 Class A Shares S000014394 Domini PacAsia Social Equity Fund C000039202 Investor Shares S000014394 Domini PacAsia Social Equity Fund C000071459 Classs A Shares