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Segment Information - Summary of Information by Reportable Segments (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Segment Reporting Information [Line Items]      
External revenues $ 14,255 $ 7,721  
Operating expenses 99,160 50,884  
Operating loss (84,905) (43,163)  
Unrestricted cash 41,678 21,897 $ 56,464
Sorrento Therapeutics      
Segment Reporting Information [Line Items]      
External revenues 7,269 2,510  
Operating expenses 81,877 33,248  
Operating loss (74,608) (30,738)  
Unrestricted cash 31,109 11,777  
Scilex      
Segment Reporting Information [Line Items]      
External revenues 6,986 5,211  
Operating expenses 17,283 17,636  
Operating loss (10,297) (12,425)  
Unrestricted cash $ 10,569 $ 10,120