Segment Information - Summary of Information by Reportable Segments (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Segment Reporting Information [Line Items]
External revenues	$ 11,461	$ 13,511	$ 29,845	$ 27,766
Operating expenses	129,822	114,061	255,089	213,221
Loss from operations	(118,361)	(100,550)	(225,244)	(185,455)
Unrestricted cash	70,345	77,291	70,345	77,291	$ 36,665
Sorrento Therapeutics
Segment Reporting Information [Line Items]
External revenues	3,535	5,709	15,107	12,978
Operating expenses	109,709	98,553	219,359	180,430
Loss from operations	(106,174)	(92,844)	(204,252)	(167,452)
Unrestricted cash	63,470	72,252	63,470	72,252
Scilex
Segment Reporting Information [Line Items]
External revenues	7,926	7,802	14,738	14,788
Operating expenses	20,113	15,508	35,730	32,791
Loss from operations	(12,187)	(7,706)	(20,992)	(18,003)
Unrestricted cash	$ 6,875	$ 5,039	$ 6,875	$ 5,039