Quarterly Financial Data (Unaudited) - Schedule of Quarterly Financial Data (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Dec. 31, 2020	Sep. 30, 2020	Jun. 30, 2020	Mar. 31, 2020	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Quarterly Financial Information Disclosure [Abstract]
Revenues	$ 13,076	$ 12,062	$ 13,511	$ 14,255	$ 11,505	$ 11,753	$ 9,007	$ 7,721	$ 52,904	$ 39,986	$ 31,432
Operating costs and expenses	127,685	113,449	114,061	99,160	82,028	94,857	56,735	50,884	454,355	284,504	290,825
Net loss (income) attributable to Sorrento	$ (144,417)	$ (119,803)	$ (166,615)	$ 2,510	$ (71,503)	$ (84,023)	$ (77,740)	$ (65,195)	$ (428,325)	$ (298,461)	$ (292,068)
Net loss per share - basic	$ (0.47)	$ (0.40)	$ (0.57)	$ 0.01	$ (0.27)	$ (0.33)	$ (0.36)	$ (0.36)	$ (1.45)	$ (1.30)	$ (2.20)
Net loss per share - diluted	$ (0.47)	$ (0.40)	$ (0.57)	$ 0.01	$ (0.27)	$ (0.33)	$ (0.36)	$ (0.36)	$ (1.45)	$ (1.30)	$ (2.35)
Weighted-average shares - basic	308,853	299,276	290,003	280,604	267,863	251,211	216,956	182,609	294,774	229,823	132,732
Weighted-average shares - diluted	308,853	299,276	290,003	297,909	267,863	257,670	216,956	182,609	294,774	229,823	140,514