X0206 3 2016-09-16 0 0000850261 Sorrento Therapeutics, Inc. SRNE 0001686530 Toledano Miranda Jayne C/O SORRENTO THERAPEUTICS, INC. 9380 JUDICIAL DRIVE SAN DIEGO CA 92121 0 1 0 0 EVP-Corporate Development Stock Options 6.93 2026-09-16 Common Stock 130000 D 32,500 of the stock options vest on September 16, 2017 and 1/48 of the remaining options shall vest following each one month period of service thereafter, subject to the reporting person's continued service to the Company through each such vesting date. /s/ Miranda Toledano 2016-10-05