X0306 4 2016-08-12 0 0000850261 Sorrento Therapeutics, Inc. SRNE 0001671595 Herde Kevin C/O SORRENTO THERAPEUTICS, INC. 9380 JUDICIAL DRIVE SAN DIEGO CA 92121 0 1 0 0 Executive VP and CFO Stock Options 6.52 2016-08-12 4 A 0 50000 0.00 A 2026-08-12 Common Stock 50000 130000 D 1/4 of the original number of shares subject to the option shall vest on August 12, 2017 and 1/48 of the original number of shares subject to the option shall vest following each one month period of service after August 12, 2017, subject to the reporting person's continued service to the Company through each such vesting date. /s/ Kevin Herde 2016-08-16