X0306 4 2016-07-11 0 0000850261 Sorrento Therapeutics, Inc. SRNE 0001549936 Marth William S C/O SORRENTO THERAPEUTICS, INC. 9380 JUDICIAL DRIVE SAN DIEGO CA 92121 1 0 0 0 Stock Options 6.44 2016-07-11 4 A 0 49000 0.00 A 2026-07-11 Common Stock 49000 182000 D 1/12 of the original number of shares subject to this option shall vest and become exercisable following each one month of service thereafter, subject to the reporting person's continued service on the issuer's board of directors on each such date. /s/ William Marth 2016-07-12