X0306 4 2017-12-09 0 0000849636 RespireRx Pharmaceuticals Inc. RSPI 0001559509 SAPIRSTEIN JAMES C/O RESPIRERX PHARMACEUTICALS INC. 126 VALLEY ROAD, SUITE C GLEN ROCK NJ 07452 1 0 0 0 Common Stock Options (to purchase shares of Common Stock) 1.45 2017-12-09 4 J 0 38114 A 2022-12-09 Common Stock 38114 38114 D Common Stock Options (to purchase shares of Common Stock) 2 2022-06-30 Common Stock 25000 25000 D Common Stock Options (to purchase shares of Common Stock) 3.9 2022-01-18 Common Stock 25000 25000 D Common Stock Options (to purchase shares of Common Stock) 7.3775 2021-03-31 Common Stock 30770 30770 D Common Stock Options (to purchase shares of Common Stock) 6.396 2022-08-18 Common Stock 9231 9231 D Common Stock Options (to purchase shares of Common Stock) 8.125 2022-06-30 Common Stock 6154 6154 D On December 9, 2017, Mr. Sapirstein forgave all of the accrued but unpaid directors fees to which he was entitled as of September 30, 2017, an aggregate of $55,000. On that date, the Company granted to Mr. Sapirstein options to purchase 38,114 shares of the Company's common stock, with a black-scholes value of $1.44 per option and an aggregate value of $55,000. These Common Stock Options vested upon issuance. These Common Stock Options vested upon issuance. These Common Stock Options vested in three installments: 25 percent on January 18, 2017 (the grant date), 25 percent on March 31, 2017, and 50 percent on June 30, 2017, and are all currently vested. The exercise price and number of shares of these securities have been adjusted to reflect the Company's 325-to-1 reverse stock split effective September 1, 2016, and are all currently vested. These Common Stock Options vested in four equal installments: 25 percent on March 31, 2016 (the grant date), 25 percent on June 30, 2016, 25 percent on September 30, 2016, and 25 percent on December 31, 2016, and are all currently vested. These Common Stock Options vested in four equal installments: 25 percent on December 31, 2015, 25 percent on March 31, 2016, 25 percent on June 30, 2016, and 25 percent on September 30, 2016, and are all currently vested. The Common Stock Options vested in three installments: 50 percent on June 30, 2015, 25 percent on September 30, 2015, and 25 percent on December 31, 2015, and are all currently vested. /s/ James E. Sapirstein 2017-12-11