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Consolidated Statement of Stockholders' Deficiency - USD ($)
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Series B Convertible Preferred Stock [Member]    
Balance beginning $ 21,703 $ 21,703
Balance beginning, shares 37,500 37,500
Sale of common stock units in private placement, net of placement agent fees of $20,000  
Sale of common stock units in private placement, net of placement agent fees of $20,000, shares  
Common stock issued in connection with unit exchanges  
Common stock issued in connection with unit exchanges, shares  
Fair value of common stock options issued for compensation  
Fair value of common stock options issued for compensation, shares  
Reclassification of non-permanent equity  
Fair value of common stock options issued for services  
Fair value of common stock options issued for services, shares  
Fair value of common stock options issued in exchange for accrued compensation and accounts payable  
Common stock issued related to extinguishment of convertible notes  
Common stock issued related to extinguishment of convertible notes, shares  
Sale of common stock units in private placement, net of escrow fees of $5,000  
Sale of common stock units in private placement, net of escrow fees of $5,000, shares  
Issuance of common stock units in exchange for note payable to officer  
Issuance of common stock units in exchange for note payable to officer, shares  
Fair value of warrants issued in connection issuance of units in exchange for note payable to officer  
Issuance of common stock to patent counsel  
Issuance of common stock to patent counsel, shares  
Fair value of original issue discount associated with warrants issued with convertible notes  
Net loss
Balance ending $ 21,703 $ 21,703
Balance ending, shares 37,500 37,500
Common Stock [Member]    
Balance beginning $ 3,065 $ 2,149
Balance beginning, shares 3,065,261 2,149,045
Sale of common stock units in private placement, net of placement agent fees of $20,000   $ 544
Sale of common stock units in private placement, net of placement agent fees of $20,000, shares   544,500
Common stock issued in connection with unit exchanges   $ 372
Common stock issued in connection with unit exchanges, shares   371,716
Fair value of common stock options issued for compensation  
Fair value of common stock options issued for compensation, shares  
Reclassification of non-permanent equity  
Fair value of common stock options issued for services  
Fair value of common stock options issued for services, shares  
Fair value of common stock options issued in exchange for accrued compensation and accounts payable  
Common stock issued related to extinguishment of convertible notes $ 284  
Common stock issued related to extinguishment of convertible notes, shares 284,358  
Sale of common stock units in private placement, net of escrow fees of $5,000 $ 191  
Sale of common stock units in private placement, net of escrow fees of $5,000, shares 191,194  
Issuance of common stock units in exchange for note payable to officer $ 48  
Issuance of common stock units in exchange for note payable to officer, shares 47,620  
Fair value of warrants issued in connection issuance of units in exchange for note payable to officer  
Issuance of common stock to patent counsel $ 284  
Issuance of common stock to patent counsel, shares 283,643  
Fair value of original issue discount associated with warrants issued with convertible notes  
Net loss
Balance ending $ 3,872 $ 3,065
Balance ending, shares 3,872,076 3,065,261
Additional Paid-in Capital [Member]    
Balance beginning $ 157,422,110 $ 151,993,550
Sale of common stock units in private placement, net of placement agent fees of $20,000   733,956
Common stock issued in connection with unit exchanges   (372)
Fair value of common stock options issued for compensation   1,927,278
Fair value of common stock options issued in exchange for accrued compensation   2,582,698
Reclassification of non-permanent equity   185,000
Fair value of common stock options issued for services 29,248  
Fair value of common stock options issued in exchange for accrued compensation and accounts payable 335,529  
Common stock issued related to extinguishment of convertible notes 318,236  
Sale of common stock units in private placement, net of escrow fees of $5,000 195,559  
Issuance of common stock units in exchange for note payable to officer 49,952  
Fair value of warrants issued in connection issuance of units in exchange for note payable to officer 49,975  
Issuance of common stock to patent counsel 198,266  
Fair value of original issue discount associated with warrants issued with convertible notes 36,347  
Net loss
Balance ending 158,635,222 157,422,110
Accumulated Deficit [Member]    
Balance beginning (161,802,262) (157,510,779)
Sale of common stock units in private placement, net of placement agent fees of $20,000  
Common stock issued in connection with unit exchanges  
Fair value of common stock options issued for compensation  
Fair value of common stock options issued in exchange for accrued compensation  
Reclassification of non-permanent equity  
Fair value of common stock options issued for services  
Fair value of common stock options issued in exchange for accrued compensation and accounts payable  
Common stock issued related to extinguishment of convertible notes  
Sale of common stock units in private placement, net of escrow fees of $5,000  
Issuance of common stock units in exchange for note payable to officer  
Fair value of warrants issued in connection issuance of units in exchange for note payable to officer  
Issuance of common stock to patent counsel  
Fair value of original issue discount associated with warrants issued with convertible notes  
Net loss (2,591,790) (4,291,483)
Balance ending (164,394,052) (161,802,262)
Balance beginning (4,355,384) (5,493,377)
Sale of common stock units in private placement, net of placement agent fees of $20,000   734,500
Common stock issued in connection with unit exchanges  
Fair value of common stock options issued for compensation   1,927,278
Fair value of common stock options issued in exchange for accrued compensation   2,582,698
Reclassification of non-permanent equity   185,000
Fair value of common stock options issued for services 29,248  
Fair value of common stock options issued in exchange for accrued compensation and accounts payable 335,529  
Common stock issued related to extinguishment of convertible notes 318,520  
Sale of common stock units in private placement, net of escrow fees of $5,000 195,750  
Issuance of common stock units in exchange for note payable to officer 50,000  
Fair value of warrants issued in connection issuance of units in exchange for note payable to officer 49,975  
Issuance of common stock to patent counsel 198,550  
Fair value of original issue discount associated with warrants issued with convertible notes 36,347  
Net loss (2,591,790) (4,291,483)
Balance ending $ (5,733,255) $ (4,355,384)