Stockholders' Deficiency (Details Narrative) - USD ($)																									12 Months Ended
	Dec. 28, 2018	Nov. 21, 2018	Sep. 12, 2018	Dec. 29, 2017	Dec. 22, 2017	Dec. 21, 2017	Dec. 13, 2017	Dec. 09, 2017	Dec. 09, 2017	Nov. 29, 2017	Oct. 25, 2017	Oct. 05, 2017	Sep. 28, 2017	Sep. 27, 2017	Aug. 29, 2017	Mar. 28, 2017	Mar. 10, 2017	Jan. 17, 2017	Mar. 31, 2016	Aug. 18, 2015	Aug. 18, 2015	Jun. 30, 2015	Mar. 18, 2014	Aug. 10, 2012	Dec. 31, 2018	Dec. 31, 2017	Sep. 30, 2018	Apr. 05, 2018	Dec. 31, 2016
Preferred stock, shares authorized																									5,000,000
Preferred stock, par value																									$ 0.001
Preferred stock, shares designated																									5,000,000
Preferred stock voting																									Cumulative Convertible Preferred Stock (non-voting, "9% Preferred Stock")
Common stock, shares outstanding																								443,205	3,872,076	3,065,261
Common stock available for future issuances																									10,641,770
Offering of common stock		$ 198,550							$ 2,475,561																	$ 734,500
Proceeds from issuance of common stock																									$ 195,750	$ 754,500
Debt conversion, shares issued																									16,460
Common stock purchase of warrants																									47,620	8,000
Debt instrument interest rate																									8.93%
Purchase price per share																								$ 18.2000				$ 1.12
Warrant exercise price																									$ 1.50	$ 2.75
Warrant expiring date																									Dec. 30, 2023	Dec. 31, 2021
Fair value of warrants																									$ 49,925	$ 27,648
Fair value of market price per share																									$ 1.00
Share granted during period																									348,827	2,688,418
Cummulative loss on extinguishment of three liabilities																									$ 339,375
Loss on extinguishment of other liabilities																									$ 11,154
Stock option period																									5 years
Stock-based compensation expense									$ 2,557,083
Sold units for aggregate cash consideration																								179,747
Fair value of common stock																								$ 3,271,402
Percentage of common stock issued																								41.00%
Issue additional contingent consideration																								56,351
Issuance of contingent shares of common stock																									6,497
Common stock, shares authorized																									65,000,000	65,000,000
Common stock, shares issued																									3,872,076	3,065,261
Number of warrants, outstanding, exercisable																									1,783,229	1,464,415			540,198
Number of common stock shares unreserved for future issuance																									50,486,154
Minimum [Member]
Stock option period																										4 years 6 months 18 days
Maximum [Member]
Stock option period																										5 years
Pier Merger Agreement [Member]
Issuance of contingent shares of common stock																									6,497
General and Administrative Expense [Member]
Stock-based compensation expense																									$ 14,248	$ 1,164,537
Research and Development Member [Member]
Stock-based compensation expense																									$ 15,000	$ 762,741
2014 Equity Plan [Member]
Share granted during period																							325,025
2015 Equity Plan [Member]
Fair value of market price per share																									$ 0.65	$ 1.14
Stock warrant intrinsic value of exercisable
Deferred compensation expense
2018 Unit Offering [Member]
Preferred stock shares issuable upon conversion, per share			$ 1.05
Offering of common stock			$ 1,500,000
Initial closing amount			250,750
Proceeds from issuance of common stock			$ 200,750
Debt conversion, shares issued			50,000
Common stock purchase of warrants			238,814
Purchase price, percentage			150.00%
Percentage of investor beneficially outstanding shares of common stock			4.99%
Redemption of warrants price per share			$ 0.001
Warrant description			The warrants are also subject to redemption by the Company at $0.001 per share upon ten (10) days written notice if the Company's common stock closes at $3.00 or more for any five (5) consecutive trading days. In total, 238,814 shares of the Company's common stock and 238,814 common stock purchase warrants were purchased.
Debt instrument principal amount			$ 100,000
Debt instrument interest rate			10.00%
Gross proceeds			$ 15,000,000
Exchange rights expiration			Dec. 31, 2018
Board of Directors [Member]
Preferred stock, shares undesignated																										3,505,800	3,505,800
Board of Directors [Member] | 2015 Stock and Stock Option Plan [Member]
Option issued to purchase number of common stock																						461,538
Stock option period																						10 years
Board of Directors [Member] | 2015 Equity Plan [Member]
Share granted during period	8,985,260							6,985,260										3,038,461	1,538,461		769,231
Board of Directors [Member] | 2015 Stock and Stock Option Plan [Member]
Share granted during period																		1,500,000
Board of Directors [Member] | 2015 Stock and Stock Option Plan [Member] | Minimum [Member]
Share granted during period																		1,538,461
Board of Directors [Member] | 2015 Stock and Stock Option Plan [Member] | Maximum [Member]
Share granted during period																		3,038,461
Board of Directors [Member] | 2015 Stock and Stock Option Plan [Member]
Share granted during period	8,985,260							6,985,260
Dr. Arnold S.Lippa [Member]
Stock-based compensation expense																				$ 300,000					$ 339,600	$ 339,600
Dr. Arnold S.Lippa [Member] | 2018 Unit Offering [Member]
Debt instrument principal amount			$ 50,000
Dr. James S. Manuso [Member] | 2018 Unit Offering [Member]
Debt instrument principal amount			$ 50,000
Officer and Director [Member]
Share granted during period																								22,651
Stock options exercise price																								$ 19.5000
Series B Convertible Preferred Stock [Member]
Preferred stock, shares authorized																									37,500	37,500
Preferred stock, par value																									$ 0.001	$ 0.001
Preferred stock, shares designated																									37,500	37,500
Preferred stock shares issuable upon conversion, per share																									$ 0.00030	$ 0.00030
Debt instrument, conversion price per share																									$ 2,208.375	$ 2,208.375
Preferred stock shares issuable upon conversion																									11	11
Preferred stock redemption amount																									$ 25,001	$ 25,001
Redeemed preferred stock price per share																									$ 0.6667	$ 0.6667
Preferred stock conversion into common stock description																									Each share of Series B Preferred Stock is convertible into approximately 0.00030 shares of common stock at an effective conversion price of $2,208.375 per share of common stock, which is subject to adjustment under certain circumstances.	Each share of Series B Preferred Stock is convertible into approximately 0.00030 shares of common stock at an effective conversion price of $2,208.375 per share of common stock, which is subject to adjustment under certain circumstances.
Offering of common stock
Series B Convertible Preferred Stock [Member] | Stock Option [Member]
Conversion of stock																									4,344,996
Series B Convertible Preferred Stock [Member] | 2014 Plan [Member]
Common stock available for future issuances																									63,236
Series B Convertible Preferred Stock [Member] | 2015 Plan [Member]
Common stock available for future issuances																									4,427,341
Series A Junior Participating Preferred Stock [Member]
Preferred stock, shares designated																									205,000	205,000
Series G 1.5% Convertible Preferred Stock [Member]
Preferred stock, shares designated																									1,700	1,700
9% Cumulative Convertible Preferred Stock [Member]
Preferred stock, shares designated																									1,250,000	1,250,000
Common Stock [Member]
Common stock, shares outstanding																									3,872,076
Common stock available for future issuances																									50,486,154
Offering of common stock																										$ 544
1st 2017 Unit Offering [Member] | Aurora Capital LLC [Member]
Cash placement agent fees																									$ 20,000
Number of warrant shares fee																									8,000
Additional paid in capital warrants																									$ 27,648
1st 2017 Unit Offering [Member] | Investors [Member]
Warrants exercisable date																									Dec. 31, 2021
Percentage of investor beneficially outstanding shares of common stock																									4.99%
Redemption of warrants price per share																									$ 0.001
Gross proceeds																$ 350,000	$ 350,000								$ 15,000,000
Purchase price per share																									$ 2.50
Warrant exercise price																									$ 2.75
Percentage of unit purchase price																									200.00%
1st 2017 Unit Offering [Member] | Subsequent Equity Financing [Member]
Purchase price per share																$ 3.80	$ 4.05
2nd 2017 Unit Offering [Member] | Investors [Member]
Warrants exercisable date																									Sep. 29, 2022
Percentage of investor beneficially outstanding shares of common stock																									4.99%
Redemption of warrants price per share																									$ 0.001
Warrant description																									The warrants are also subject to redemption by the Company at $0.001 per share upon ten (10) days written notice if the Company's common stock closes at 250% or more of the unit purchase price for any five (5) consecutive trading days.
Gross proceeds				$ 404,500	$ 404,500	$ 404,500	$ 404,500			$ 404,500	$ 404,500	$ 404,500	$ 404,500	$ 404,500	$ 404,500										$ 15,000,000
Purchase price per share				$ 1.14	$ 1.45	$ 1.51	$ 1.45			$ 1.05	$ 0.80	$ 1.50	$ 1.40	$ 1.40	$ 1.00										$ 1.00
Warrant exercise price																									$ 1.10
Percentage of unit purchase price																									250.00%
Common Stock Warrants [Member]
Fair value of market price per share																									$ 0.68	$ 1.14
Stock warrant intrinsic value of exercisable																										$ 128,270