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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Cash flows from operating activities:    
Net loss $ (1,917,817) $ (3,671,753)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 4,860
Stock-based compensation expense included in - General and administrative expenses 14,248 1,150,925
Stock-based compensation expense included in - Research and development expenses 606,901
Foreign currency transaction loss 108,582 30,728
Loss on extinguishment of debt 116,407
Loss on extinguishment of other liabilities 11,154
(Increase) decrease in -    
Prepaid expenses (13,030) 5,599
Increase (decrease) in -    
Accounts payable and accrued expenses 456,302 463,510
Accrued compensation and related expenses 836,849 812,874
Notes payable and accrued interest 198,493 75,540
Short-term note payable 24,999
Net cash used in operating activities (199,966) (495,817)
Cash flows from financing activities:    
Proceeds from sale of common stock units 200,750 476,000
Placement agent and other offering fees (5,000) (20,000)
Net cash provided by financing activities 195,750 456,000
Cash and cash equivalents:    
Net (decrease) increase (4,216) (39,817)
Balance at beginning of period 84,902 92,040
Balance at end of period 80,686 52,223
Supplemental disclosures of cash flow information:    
Interest 2,802 2,133
Non-cash financing activities:    
10% convertible notes payable, including accrued interest of $62,267, exchanged for common stock 213,266
Accounts payable and accrued expenses extinguished with common stock options 335,529
Officer note payable, exchanged for common stock units 50,000
Accrual of fees payable to placement agent in connection with the sale of common stock units 20,000
Fair value of common stock warrants issued to placement agent in connection with the sale of common stock units 27,648
Reclassification of non-permanent equity $ 185,000