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Consolidated Balance Sheets - USD ($)
Dec. 31, 2015
Dec. 31, 2014
Current assets:    
Cash and cash equivalents $ 53,199 $ 162,752
Grant receivable 48,000
Deferred and capitalized financing costs $ 3,429 85,702
Prepaid expenses, including current portion of long-term prepaid insurance of $14,945 at December 31, 2015 and 2014 29,144 24,219
Total current assets 85,772 320,673
Equipment, net of accumulated depreciation of $8,776 and $1,659 at December 31, 2015 and 2014, respectively 12,121 16,741
Long-term prepaid insurance, net of current portion of $14,945 at December 31, 2015 and 2014 47,949 62,894
Total assets 145,842 400,308
Current liabilities:    
Accounts payable and accrued expenses, including $111,688 and $108,375 payable to related parties at December 31, 2015 and 2014, respectively 1,434,429 1,845,875
Accrued compensation and related expenses $ 710,409 144,000
Unearned grant revenues 34,333
10% convertible notes payable, including accrued interest of $61,388 and $4,093, net of unamortized discounts of $342,932 and $323,350 at December 31, 2015 and 2014, respectively $ 297,956 50,243
Note payable to related party, including accrued interest of $171,257 and $122,618 at December 31, 2015 and 2014, respectively 561,568 $ 526,257
Other short-term note payable, including accrued interest of $8 3,689
Total current liabilities $ 3,008,051 $ 2,600,708
Commitments and contingencies (Note 9)
Stockholders' deficiency:    
Common stock, $0.001 par value; shares authorized: 1,400,000,000; shares issued and outstanding: 489,846,883 and 232,145,326 at December 31, 2015 and 2014, respectively $ 489,847 $ 232,145
Additional paid-in capital 144,647,529 138,984,110
Accumulated deficit (148,279,854) (142,311,095)
Total stockholders' deficiency (2,862,209) (2,200,400)
Total liabilities and stockholders' deficiency 145,842 400,308
Series B Convertible Preferred Stock [Member]    
Stockholders' deficiency:    
Preferred stock value 21,703 21,703
Series G 1.5% Cumulative Mandatorily Convertible Preferred Stock [Member]    
Stockholders' deficiency:    
Preferred stock value $ 258,566 $ 872,737