<?xml version="1.0" encoding="UTF-8"?>
<edgarSubmission xmlns="http://www.sec.gov/edgar/seventeenafiler" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>X-17A-5</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <filerCik>0000846416</filerCik>
          <filerCcc>XXXXXXXX</filerCcc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>
      <flags>
        <returnCopyFlag>true</returnCopyFlag>
        <confirmingCopyFlag>false</confirmingCopyFlag>
        <overrideInternetFlag>false</overrideInternetFlag>
      </flags>
    </filerInfo>
  </headerData>
  <formData>
    <submissionInformation>
      <periodBegin>01-01-2018</periodBegin>
      <periodEnd>12-31-2018</periodEnd>
      <typeOfRegistrant>Broker-dealer</typeOfRegistrant>
      <materialWeakness>N</materialWeakness>
    </submissionInformation>
    <registrantIdentification>
      <brokerDealerName>L.O. THOMAS &amp; CO. INC.</brokerDealerName>
      <businessAddress>
        <com:street1>LINWOOD COMMONS-SUITE A-6</com:street1>
        <com:street2>2106 NEW ROAD</com:street2>
        <com:city>LINWOOD</com:city>
        <com:stateOrCountry>NJ</com:stateOrCountry>
        <com:zipCode>08221</com:zipCode>
      </businessAddress>
      <contactPersonName>John W. Risley Jr.</contactPersonName>
      <contactPersonPhoneNumber>6099274044</contactPersonPhoneNumber>
    </registrantIdentification>
    <accountantIdentification>
      <accountantName>Michael T. Remus</accountantName>
      <accountantAddress>
        <com:street1>100 Horizon Center Blvd</com:street1>
        <com:city>Hamilton Square</com:city>
        <com:stateOrCountry>NJ</com:stateOrCountry>
        <com:zipCode>08690</com:zipCode>
      </accountantAddress>
      <accountantType>Certified Public Accountant</accountantType>
    </accountantIdentification>
    <oathSignature>
      <signPersonName>John W. Risley Jr.</signPersonName>
      <entityName>L.O. THOMAS &amp; CO. INC.</entityName>
      <signDate>02-28-2019</signDate>
      <signature>John W. Risley Jr.</signature>
      <oathTitle>President/CCO</oathTitle>
      <confirmNotarizedFlag>Y</confirmNotarizedFlag>
    </oathSignature>
  </formData>
</edgarSubmission>
