Stockholders' Equity (Details 1) - shares	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Securities excluded from calculation of dilutive loss per share	595,157,254,028	591,425,774,123
Stock options [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Securities excluded from calculation of dilutive loss per share	89,268,899,200	82,851,011,360
Warrants [Member]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Securities excluded from calculation of dilutive loss per share	505,888,354,828	508,574,762,763