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      <invstOrSec>
        <name>Cigna Corp</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>AGILENT TECHNOLOGIES INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Immunocore Holdings PLC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Cerevel Therapeutics Holdings</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Dexcom Inc</name>
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        <name>Enanta Pharmaceuticals Inc</name>
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        <name>Rhythm Pharmaceuticals Inc</name>
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        <name>Immuneering Corp</name>
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        <name>BRISTOL-MYERS SQUIBB CO</name>
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        <name>Novocure Ltd</name>
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        <name>MoonLake Immunotherapeutics</name>
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        <name>THERMO FISHER SCIENTIFIC INC</name>
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        <name>West Pharmaceutical Services I</name>
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        <name>AmerisourceBergen Corp</name>
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        <name>Genmab A/S</name>
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        <name>UBS Securities LLC</name>
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        <name>Alkermes PLC</name>
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        <name>BIOMARIN PHARMACEUTICAL INC</name>
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        <name>Sanofi</name>
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        <title>Sanofi</title>
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        <name>CENTENE CORP</name>
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        <name>Carbon Health Technologies Inc.</name>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>Insulet Corp</name>
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      <invstOrSec>
        <name>TScan Therapeutics Inc</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Regeneron Pharmaceuticals Inc</name>
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        <fairValLevel>1</fairValLevel>
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        <name>iRhythm Technologies Inc</name>
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        <fairValLevel>1</fairValLevel>
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        <name>SAREPTA THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>CAREMAX INC</name>
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        <name>LHC Group Inc</name>
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        <name>Daiichi Sankyo Co Ltd</name>
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        <name>ABIOMED Inc</name>
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        <name>Catalent Inc</name>
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        <name>Horizon Therapeutics Plc</name>
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        <name>INCYTE CORP</name>
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        <name>Cellarity, Inc. series B</name>
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        <name>Bausch + Lomb Corp</name>
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        <name>BOSTON SCIENTIFIC CORP</name>
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        <name>Affinivax Inc.,</name>
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        <name>Alnylam Pharmaceuticals Inc</name>
        <lei>529900S3ZI14OWRJII50</lei>
        <title>Alnylam Pharmaceuticals Inc</title>
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        <name>ICON PLC</name>
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        <title>ICON PLC</title>
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        <name>Design Therapeutics Inc</name>
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        <name>Biogen Inc</name>
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        <name>RESMED INC</name>
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        <name>Mirati Therapeutics Inc</name>
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        <fairValLevel>1</fairValLevel>
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        <name>STRYKER CORP</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Exact Sciences Corp</name>
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        <fairValLevel>1</fairValLevel>
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        <name>IsoPlexis Corp</name>
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        <fairValLevel>1</fairValLevel>
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        <name>ZOETIS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>AbbVie Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Roche Holding AG</name>
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        <fairValLevel>2</fairValLevel>
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        <name>Hansoh Pharmaceutical Group Co</name>
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        <name>Encompass Health Corp</name>
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        <name>Rocket Pharmaceuticals Inc</name>
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        <name>Quanta Dialysis Technologies Ltd SERIES D</name>
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        <name>Johnson &amp; Johnson</name>
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        <name>Legend Biotech Corp</name>
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        <name>Ultragenyx Pharmaceutical Inc</name>
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        <name>Monte Rosa Therapeutics Inc</name>
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        <name>GILEAD SCIENCES INC</name>
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        <name>ABBOTT LABORATORIES</name>
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        <name>LARONDE INC SERIES B</name>
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        <name>Argenx SE</name>
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        <name>MERCK &amp; CO INC</name>
        <lei>4YV9Y5M8S0BRK1RP0397</lei>
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      <invstOrSec>
        <name>Penumbra Inc</name>
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      <invstOrSec>
        <name>Rapid Micro Biosystems Inc</name>
        <lei>N/A</lei>
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          <isin value="US75340L1044"/>
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        <curCd>USD</curCd>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Karuna Therapeutics Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Mettler-Toledo International I</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Cooper Cos Inc/The</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>10X Genomics Inc</name>
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      <invstOrSec>
        <name>Genmab A/S</name>
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      <invstOrSec>
        <name>Prime Medicine Inc</name>
        <lei>N/A</lei>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Omnicell Inc</name>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>HCA Healthcare Inc</name>
        <lei>529900PH4ZGUH2MNEU89</lei>
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          <isin value="US40412C1018"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>REVOLUTION Medicines Inc</name>
        <lei>549300JU3X0LBCQ65892</lei>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>BAXTER INTERNATIONAL INC</name>
        <lei>J5OIVXX3P24RJRW5CK77</lei>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Seagen Inc</name>
        <lei>N/A</lei>
        <title>Seagen Inc</title>
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        <assetCat>EC</assetCat>
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        <name>Glaukos Corp</name>
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        <name>EDWARDS LIFESCIENCES CORP</name>
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        <name>AMGEN INC</name>
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        <name>ANTHEM INC</name>
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        <name>Decibel Therapeutics Inc</name>
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        <name>Waters Corp</name>
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        <name>MONEY MARKET SERIES LLC</name>
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        <name>Prothena Corp PLC</name>
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        <title>Prothena Corp PLC</title>
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        <invCountry>IE</invCountry>
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        <name>Arvinas Inc</name>
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        <name>Nuvalent Inc</name>
        <lei>N/A</lei>
        <title>Nuvalent Inc</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Insitro, Series C</name>
        <lei>N/A</lei>
        <title>Insitro, Series C</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="INTERNAL" value="BRWH9E7P6"/>
        </identifiers>
        <balance>592636.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7046442.04000000</valUSD>
        <pctVal>0.074032786100</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BioNTech SE</name>
        <lei>894500UZJ5LG1F8J1U58</lei>
        <title>BioNTech SE</title>
        <cusip>09075V102</cusip>
        <identifiers>
          <isin value="US09075V1026"/>
          <ticker value="BNTX"/>
        </identifiers>
        <balance>137130.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>22903452.60000000</valUSD>
        <pctVal>0.240632988632</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INTUITIVE SURGICAL INC</name>
        <lei>54930052SRG011710797</lei>
        <title>INTUITIVE SURGICAL INC</title>
        <cusip>46120E602</cusip>
        <identifiers>
          <isin value="US46120E6023"/>
          <ticker value="ISRG"/>
        </identifiers>
        <balance>717534.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>194014018.26000000</valUSD>
        <pctVal>2.038390187968</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AstraZeneca PLC</name>
        <lei>PY6ZZQWO2IZFZC3IOL08</lei>
        <title>AstraZeneca PLC</title>
        <cusip>046353108</cusip>
        <identifiers>
          <isin value="US0463531089"/>
          <ticker value="AZN"/>
        </identifiers>
        <balance>398642.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>27095696.74000000</valUSD>
        <pctVal>0.284678410695</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>J.P. MORGAN SECURITIES LLC</name>
        <lei>ZBUT11V806EZRVTWT807</lei>
        <title>USD/GBP FORWARD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <ticker value="N/A"/>
          <other otherDesc="INTERNAL" value="MDJ2210250503232"/>
        </identifiers>
        <balance>1.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>2344328.34000000</valUSD>
        <pctVal>0.024630467058</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DFE</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <fwdDeriv derivCat="FWD">
            <counterparties>
              <counterpartyName>J.P. MORGAN SECURITIES LLC</counterpartyName>
              <counterpartyLei>ZBUT11V806EZRVTWT807</counterpartyLei>
            </counterparties>
            <amtCurSold>-47204831.16000000</amtCurSold>
            <curSold>USD</curSold>
            <amtCurPur>41086000.00000000</amtCurPur>
            <curPur>GBP</curPur>
            <settlementDt>2022-12-15</settlementDt>
            <unrealizedAppr>2344328.34000000</unrealizedAppr>
          </fwdDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UNITEDHEALTH GROUP INC</name>
        <lei>549300GHBMY8T5GXDE41</lei>
        <title>UNITEDHEALTH GROUP INC</title>
        <cusip>91324P102</cusip>
        <identifiers>
          <isin value="US91324P1021"/>
          <ticker value="UNH"/>
        </identifiers>
        <balance>1517369.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>831154043.44000000</valUSD>
        <pctVal>8.732442439124</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Sage Therapeutics Inc</name>
        <lei>5493000JX4BJS9W6CN35</lei>
        <title>Sage Therapeutics Inc</title>
        <cusip>78667J108</cusip>
        <identifiers>
          <isin value="US78667J1088"/>
          <ticker value="SAGE"/>
        </identifiers>
        <balance>343935.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>14115092.40000000</valUSD>
        <pctVal>0.148298901844</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="2684016.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Zimmer Biomet Holdings Inc</name>
        <lei>2P2YLDVPES3BXQ1FRB91</lei>
        <title>Zimmer Biomet Holdings Inc</title>
        <cusip>98956P102</cusip>
        <identifiers>
          <isin value="US98956P1021"/>
          <ticker value="ZBH"/>
        </identifiers>
        <balance>239113.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>28717471.30000000</valUSD>
        <pctVal>0.301717433854</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IQVIA Holdings Inc</name>
        <lei>549300W3R20NM4KQPH86</lei>
        <title>IQVIA Holdings Inc</title>
        <cusip>46266C105</cusip>
        <identifiers>
          <isin value="US46266C1053"/>
          <ticker value="IQV"/>
        </identifiers>
        <balance>394897.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>86095443.94000000</valUSD>
        <pctVal>0.904553751991</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Quest Diagnostics Inc</name>
        <lei>8MCWUBXQ0WE04KMXBX50</lei>
        <title>Quest Diagnostics Inc</title>
        <cusip>74834L100</cusip>
        <identifiers>
          <isin value="US74834L1008"/>
          <ticker value="DGX"/>
        </identifiers>
        <balance>647908.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>98371871.64000000</valUSD>
        <pctVal>1.033534894650</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>J.P. MORGAN SECURITIES LLC</name>
        <lei>ZBUT11V806EZRVTWT807</lei>
        <title>USD/EUR FORWARD</title>
        <cusip>000000000</cusip>
        <identifiers>
          <ticker value="N/A"/>
          <other otherDesc="INTERNAL" value="MDJ2210250504752"/>
        </identifiers>
        <balance>1.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>583719.53000000</valUSD>
        <pctVal>0.006132794800</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DFE</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <derivativeInfo>
          <fwdDeriv derivCat="FWD">
            <counterparties>
              <counterpartyName>J.P. MORGAN SECURITIES LLC</counterpartyName>
              <counterpartyLei>ZBUT11V806EZRVTWT807</counterpartyLei>
            </counterparties>
            <amtCurSold>-13678481.21000000</amtCurSold>
            <curSold>USD</curSold>
            <amtCurPur>13687000.00000000</amtCurPur>
            <curPur>EUR</curPur>
            <settlementDt>2022-12-15</settlementDt>
            <unrealizedAppr>583719.53000000</unrealizedAppr>
          </fwdDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Sigilon Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>Sigilon Therapeutics Inc</title>
        <cusip>82657L107</cusip>
        <identifiers>
          <isin value="US82657L1070"/>
          <ticker value="SGTX"/>
        </identifiers>
        <balance>332626.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>138605.25000000</valUSD>
        <pctVal>0.001456243131</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="500.04000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Ionis Pharmaceuticals Inc</name>
        <lei>549300SI4ZGLG0BLUZ92</lei>
        <title>Ionis Pharmaceuticals Inc</title>
        <cusip>462222100</cusip>
        <identifiers>
          <isin value="US4622221004"/>
          <ticker value="IONS"/>
        </identifiers>
        <balance>293400.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>11967786.00000000</valUSD>
        <pctVal>0.125738427423</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Afferent Pharmaceuticals, Inc.</name>
        <lei>N/A</lei>
        <title>Afferent Pharmaceuticals, Inc.</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal" value="BRSUB0VG2"/>
        </identifiers>
        <balance>3420640.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2599686.40000000</valUSD>
        <pctVal>0.027313362699</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PMV Pharmaceuticals Inc</name>
        <lei>N/A</lei>
        <title>PMV Pharmaceuticals Inc</title>
        <cusip>69353Y103</cusip>
        <identifiers>
          <isin value="US69353Y1038"/>
          <ticker value="PMVP"/>
        </identifiers>
        <balance>306148.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3055357.04000000</valUSD>
        <pctVal>0.032100823780</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="1245504.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Moderna Inc</name>
        <lei>549300EI6OKH5K5Q2G38</lei>
        <title>Moderna Inc</title>
        <cusip>60770K107</cusip>
        <identifiers>
          <isin value="US60770K1079"/>
          <ticker value="MRNA"/>
        </identifiers>
        <balance>570284.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>100318658.44000000</valUSD>
        <pctVal>1.053988628596</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="23096983.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Medtronic PLC</name>
        <lei>549300GX3ZBSQWUXY261</lei>
        <title>Medtronic PLC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="IE00BTN1Y115"/>
          <ticker value="MDT"/>
          <other otherDesc="SEDOL" value="BTN1Y11"/>
        </identifiers>
        <balance>2002837.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>158304236.48000000</valUSD>
        <pctVal>1.663208696199</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELI LILLY &amp; CO</name>
        <lei>FRDRIPF3EKNDJ2CQJL29</lei>
        <title>ELI LILLY &amp; CO</title>
        <cusip>532457108</cusip>
        <identifiers>
          <isin value="US5324571083"/>
          <ticker value="LLY"/>
        </identifiers>
        <balance>1425371.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>528926670.68000000</valUSD>
        <pctVal>5.557118734710</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="72731680.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Tenaya Therapeutics Inc</name>
        <lei>N/A</lei>
        <title>Tenaya Therapeutics Inc</title>
        <cusip>87990A106</cusip>
        <identifiers>
          <isin value="US87990A1060"/>
          <ticker value="TNYA"/>
        </identifiers>
        <balance>431076.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1142351.40000000</valUSD>
        <pctVal>0.012002008441</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>BLACKROCK LIQUIDITY FUNDS T-FUND PORTFOLIO</name>
        <lei>5493002L9DNZ83RX7V61</lei>
        <title>BLACKROCK LIQUIDITY FUNDS T-FUND PORTFOLIO</title>
        <cusip>09248U718</cusip>
        <identifiers>
          <isin value="US09248U7182"/>
          <ticker value="TSTXX"/>
        </identifiers>
        <balance>175058791.47000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>175058791.47000000</valUSD>
        <pctVal>1.839238865574</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>QIAGEN NV</name>
        <lei>54930036WK3GMCN17Z57</lei>
        <title>QIAGEN NV</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="NL0012169213"/>
          <ticker value="QGEN"/>
          <other otherDesc="SEDOL" value="BYXS688"/>
        </identifiers>
        <balance>406956.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>20160600.24000000</valUSD>
        <pctVal>0.211815466126</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>





      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2023-01-24</ncom:dateSigned>
      <ncom:nameOfApplicant>BlackRock Funds</ncom:nameOfApplicant>
      <ncom:signature>Ann Frechette</ncom:signature>
      <ncom:signerName>Ann Frechette</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
