NPORT-P false 0000844779 XXXXXXXX S000001877 C000037661 C000004916 C000172900 C000004913 C000004914 C000004912 BlackRock Funds 811-05742 0000844779 549300OZUEVJZHOBFP42 100 Bellevue Parkway Wilmington 19809 800-441-7762 BlackRock Health Sciences Opportunities Portfolio S000001877 VN6DJGBO8DKY0GTM4883 2022-05-31 2021-11-30 N 10867245920.09 258798225.35 10608447694.74 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 N Arcutis Biotherapeutics Inc N/A 03969K108 799932.00000000 NS USD 13254873.24000000 0.124946397639 Long EC CORP US N 1 N N N Innovage Holding Corp N/A 45784A104 249456.00000000 NS USD 1988164.32000000 0.018741331222 Long EC CORP US N 1 N N PTC Therapeutics Inc 549300UJLWOIWFDGB318 69366J200 87333.00000000 NS USD 3245294.28000000 0.030591603723 Long EC CORP US N 1 N N N Natera Inc N/A 632307104 540705.00000000 NS USD 49452879.30000000 0.466165085816 Long EC CORP US N 1 N N N RESMED INC 529900T3QE5253CCXF22 761152107 332327.00000000 NS USD 84693535.95000000 0.798359367808 Long EC CORP US N 1 N N N TELEFLEX INC UUL85LWXB4NGSWWXIQ25 879369106 328562.00000000 NS USD 97720910.04000000 0.921161256122 Long EC CORP US N 1 N N N AGILENT TECHNOLOGIES INC QUIX8Y7A2WP0XRMW7G29 00846U101 252798.00000000 NS USD 38147218.20000000 0.359592838629 Long EC CORP US N 1 N N N Rapid Micro Biosystems Inc N/A 75340L104 377456.00000000 NS USD 4650257.92000000 0.043835422993 Long EC CORP US N 1 N N AMBRX BIOPHARMA INC N/A 000000000 5895041.00000000 NS USD 7841282.89000000 0.073915459788 Long EC CORP US Y 2 N N N Immunocore Holdings PLC 213800IUE3DFS84BVN18 45258D105 181355.00000000 NS USD 6526966.45000000 0.061526121802 Long EC CORP GB N 1 N N Genmab A/S 529900MTJPDPE4MHJ122 000000000 95810.00000000 NS 37130392.67000000 0.350007783781 Long EC CORP DK N 2 N N N Tenaya Therapeutics Inc N/A 87990A106 558966.00000000 NS USD 10983681.90000000 0.103537126411 Long EC CORP US N 1 N N N ABBOTT LABORATORIES HQD377W2YR662HK5JX27 002824100 4589918.00000000 NS USD 577273986.86000000 5.441644277006 Long EC CORP US N 1 N N N Quanta Dialysis Technologies Ltd SERIES D N/A 000000000 80024425.00000000 NS 9363258.74000000 0.088262288785 Long EC CORP GB Y 3 N N N Mirati Therapeutics Inc 529900GYRW59IDQV6N54 60468T105 158735.00000000 NS USD 21710185.95000000 0.204649978721 Long EC CORP US N 1 N N Imago Biosciences Inc N/A 45250K107 453999.00000000 NS USD 10155957.63000000 0.095734625104 Long EC CORP US N 1 N N Cerevel Therapeutics Holdings N/A 15678U128 312854.00000000 NS USD 9757916.26000000 0.091982508099 Long EC CORP US N 1 N N IQVIA Holdings Inc 549300W3R20NM4KQPH86 46266C105 572317.00000000 NS USD 148304504.21000000 1.397984968936 Long EC CORP US N 1 N N N STRYKER CORP 5493002F0SC4JTBU5137 863667101 770160.00000000 NS USD 182242960.80000000 1.717904127390 Long EC CORP US N 1 N N N Privia Health Group Inc N/A 74276R102 300406.00000000 NS USD 6939378.60000000 0.065413704244 Long EC CORP US N 1 N N Alignment Healthcare Inc N/A 01625V104 922645.00000000 NS USD 14956075.45000000 0.140982694927 Long EC CORP US N 1 N N Point Biopharma Global Inc N/A 730541109 499734.00000000 NS USD 4032853.38000000 0.038015490070 Long EC CORP US N 1 N N Exo Imaging, Inc. SERIES C N/A 000000000 1908330.00000000 NS USD 11169770.36000000 0.105291279944 Long EC CORP US Y 3 N N N Agios Pharmaceuticals Inc 529900ONJHY8EOGYT555 00847X104 402443.00000000 NS USD 14335019.66000000 0.135128343679 Long EC CORP US N 1 N N Dicerna Pharmaceuticals Inc 549300CTZMJMPH28WN39 253031108 265086.00000000 NS USD 10075918.86000000 0.094980143654 Long EC CORP US N 1 N N N BAXTER INTERNATIONAL INC J5OIVXX3P24RJRW5CK77 071813109 1734891.00000000 NS USD 129370821.87000000 1.219507562205 Long EC CORP US N 1 N N N HEALTH ASSURANCE ACQUISITION CORP N/A 42226W117 441399.00000000 NC USD 445812.99000000 0.004202433785 N/A DE CORP US N 1 HEALTH ASSURANCE ACQUISITION CORP N/A Call Purchased Health Assurance Acquisition C Health Assurance Acquisition Corp 1.00000000 11.50000000 USD 2025-11-12 XXXX -1159272.68000000 N N N Roche Holding AG 549300U41AUUVOAAOB37 000000000 210643.00000000 NS 82237207.17000000 0.775204907790 Long EC CORP CH N 2 N N N Guardant Health Inc 254900M8C3E5VC8BR186 40131M109 175419.00000000 NS USD 18440045.28000000 0.173824161749 Long EC CORP US N 1 N N Argenx SE 7245009C5FZE6G9ODQ71 04016X101 130612.00000000 NS USD 36468176.52000000 0.343765436465 Long EC CORP NL N 1 N N N Nektar Therapeutics 5299005I24806IOIYE03 640268108 411217.00000000 NS USD 4630303.42000000 0.043647322899 Long EC CORP US N 1 N N N MASIMO CORP 549300Q4A8JK0PIYCU29 574795100 411642.00000000 NS USD 114485873.04000000 1.079195338793 Long EC CORP US N 1 N N N VERTEX PHARMACEUTICALS INC 54930015RAQRRZ5ZGJ91 92532F100 478258.00000000 NS USD 89405550.52000000 0.842776936764 Long EC CORP US N 1 N N N Acumen Pharmaceuticals Inc N/A 00509G209 772313.00000000 NS USD 6101272.70000000 0.057513341023 Long EC CORP US N 1 N N Connect Biopharma Holdings Ltd N/A 207523101 662152.34000000 NS USD 2880362.68000000 0.027151594303 Long EC CORP CN N 1 N N Health Sciences Acquisitions C N/A 000000000 262308.00000000 NS USD 2588979.96000000 0.024404889711 Long EC CORP US N 1 N N N Insulet Corp 549300TZTYD2PYN92D43 45784P101 105936.00000000 NS USD 30556179.84000000 0.288036296348 Long EC CORP US N 1 N N Taysha Gene Therapies Inc N/A 877619106 577643.00000000 NS USD 7497806.14000000 0.070677693435 Long EC CORP US N 1 N N N BRISTOL-MYERS SQUIBB CO HLYYNH7UQUORYSJQCN42 110122108 889150.00000000 NS USD 47685114.50000000 0.449501339612 Long EC CORP US N 1 N N N INCYTE CORP 549300Z4WN6JVZ3T4680 45337C102 421332.00000000 NS USD 28532603.04000000 0.268961151160 Long EC CORP US N 1 N N N Everest Medicines Ltd 3003005FQADBCG83AX84 000000000 576500.00000000 NS 2603261.23000000 0.024539511386 Long EC CORP CN N 2 N N N Sanofi 549300E9PC51EN656011 000000000 1044116.00000000 NS 99256074.32000000 0.935632405193 Long EC CORP FR N 2 N N N Regeneron Pharmaceuticals Inc 549300RCBFWIRX3HYQ56 75886F107 214112.00000000 NS USD 136288711.36000000 1.284718700433 Long EC CORP US N 1 N N N Swift Health Systems Inc., SERIES D N/A 000000000 1700345.00000000 NS USD 5254066.05000000 0.049527190039 Long EC CORP US Y 3 N N N LARONDE INC SERIES B N/A 000000000 386520.00000000 NS USD 10822560.00000000 0.102018318904 Long EC CORP US Y 3 N N N Horizon Therapeutics Plc 529900P0GSQ79OOZEV53 000000000 360944.00000000 NS USD 37451549.44000000 0.353035151962 Long EC CORP US N 1 N N HUMANA INC 529900YLDW34GJAO4J06 444859102 419605.00000000 NS USD 176112414.55000000 1.660114840716 Long EC CORP US N 1 N N N Neurogene, Inc. Series B N/A 000000000 2090000.00000000 NS USD 5789300.00000000 0.054572546017 Long EC CORP US Y 3 N N N TScan Therapeutics Inc N/A 89854M101 551194.00000000 NS USD 4299313.20000000 0.040527260195 Long EC CORP US N 1 N N REVOLUTION Medicines Inc 549300JU3X0LBCQ65892 76155X100 191455.00000000 NS USD 5295645.30000000 0.049919134753 Long EC CORP US N 1 N N Enanta Pharmaceuticals Inc 529900SSN4DODDQSN594 29251M106 57153.00000000 NS USD 5045466.84000000 0.047560840051 Long EC CORP US N 1 N N N Monte Rosa Therapeutics Inc N/A 61225M102 533603.00000000 NS USD 10346562.17000000 0.097531349239 Long EC CORP US N 1 N N GILEAD SCIENCES INC 549300WTZWR07K8MNV44 375558103 2439663.00000000 NS USD 168165970.59000000 1.585208085376 Long EC CORP US N 1 N N N West Pharmaceutical Services I 5493007NKRGM1RJQ1P16 955306105 39935.00000000 NS USD 17677627.10000000 0.166637265023 Long EC CORP US N 1 N N N MEDTECH ACQUISITION CORP/NY N/A 58507N113 277207.00003000 NC USD 360369.10000000 0.003397001242 N/A DE CORP US N 1 MEDTECH ACQUISITION CORP/NY N/A Call Purchased MedTech Acquisition Corp/NY MedTech Acquisition Corp/NY 1.00000000 11.50000000 USD 2025-12-18 XXXX -245641.46000000 N N N ELI LILLY & CO FRDRIPF3EKNDJ2CQJL29 532457108 1401035.00000000 NS USD 347512721.40000000 3.275811234590 Long EC CORP US N 1 N N N Cooper Cos Inc/The QJKMVPIGLH7530PCUE20 216648402 64495.00000000 NS USD 24280432.65000000 0.228878280297 Long EC CORP US N 1 N N N agilon health Inc N/A 00857U107 772691.00000000 NS USD 16999202.00000000 0.160242124853 Long EC CORP US N 1 N N N Danaher Corp S4BKK9OTCEWQ3YHPFM11 235851102 673104.00000000 NS USD 216497170.56000000 2.040799717260 Long EC CORP US N 1 N N N CAREMAX CORP N/A 000000000 500000.00000000 NS USD 3350000.00000000 0.031578606940 Long EC CORP US Y 2 N N N QIAGEN NV 54930036WK3GMCN17Z57 000000000 602770.00000000 NS USD 33230710.10000000 0.313247621671 Long EC CORP NL N 1 N N N EDWARDS LIFESCIENCES CORP YA13X31F3V31L8TMPR58 28176E108 1702541.00000000 NS USD 182699674.71000000 1.722209318151 Long EC CORP US N 1 N N N Twist Bioscience Corp 549300T23BL59LCOH584 90184D100 68280.00000000 NS USD 6520740.00000000 0.061467428483 Long EC CORP US N 1 N N Cigna Corp 549300VIWYMSIGT1U456 125523100 1297641.00000000 NS USD 249017307.90000000 2.347349160457 Long EC CORP US N 1 N N N Alcon Inc 549300LDT5AP8S0NBM78 000000000 1055156.00000000 NS USD 82724230.40000000 0.779795807835 Long EC CORP CH N 1 N N Agiliti Inc N/A 00848J104 1425142.00000000 NS USD 30013490.52000000 0.282920662698 Long EC CORP US N 1 N N APELLIS PHARMACEUTICALS INC 254900HS0ZFRXXSB9D42 03753U106 286228.00000000 NS USD 12044474.24000000 0.113536632187 Long EC CORP US N 1 N N AstraZeneca PLC PY6ZZQWO2IZFZC3IOL08 000000000 919850.00000000 NS 100847615.41000000 0.950634987435 Long EC CORP GB N 2 N N N Alnylam Pharmaceuticals Inc 529900S3ZI14OWRJII50 02043Q107 622346.00000000 NS USD 114387194.80000000 1.078265153314 Long EC CORP US N 1 N N Tandem Diabetes Care Inc 549300JEPFOD0K4D3I05 875372203 163435.00000000 NS USD 21004666.20000000 0.197999432192 Long EC CORP US N 1 N N N PFIZER INC 765LHXWGK1KXCLTFYQ30 717081103 12944312.00000000 NS USD 695497883.76000000 6.556075910190 Long EC CORP US N 1 N N N SAREPTA THERAPEUTICS INC 549300IKDPIED8J8IG21 803607100 160519.00000000 NS USD 12971540.39000000 0.122275574742 Long EC CORP US N 1 N N N BLUEPRINT MEDICINES CORP 5299004CC60O9T5HVM83 09627Y109 208668.00000000 NS USD 20073861.60000000 0.189225249326 Long EC CORP US N 1 N N N Moderna Inc 549300EI6OKH5K5Q2G38 60770K107 430850.00000000 NS USD 151844465.50000000 1.431354236447 Long EC CORP US N 1 N N Decibel Therapeutics Inc. N/A 000000000 424528.00000000 NS USD 2929243.20000000 0.027612364073 Long EC CORP US N 2 N N N Johnson & Johnson 549300G0CFPGEF6X2043 478160104 2532085.00000000 NS USD 394828014.05000000 3.721826467087 Long EC CORP US N 1 N N N THERMO FISHER SCIENTIFIC INC HCHV7422L5HDJZCRFL38 883556102 1078097.00000000 NS USD 682252124.51000000 6.431215425120 Long EC CORP US N 1 N N N Kronos Bio Inc N/A 50107A104 312693.00472400 NS USD 3692904.39000000 0.034810977970 Long EC CORP US N 1 N N Oak Street Health Inc 2549007CJE6GSEURLA30 67181A107 921279.00000000 NS USD 28513585.05000000 0.268781879031 Long EC CORP US N 1 N N ICON PLC 6354008SRQGEMC4XFI67 000000000 268965.00000000 NS USD 72746963.55000000 0.685745602403 Long EC CORP IE N 1 N N Bridgebio Pharma Inc 54930028YG89VTY2J114 10806X102 111005.00000000 NS USD 4495702.50000000 0.042378514080 Long EC CORP US N 1 N N N Afferent Pharmaceuticals, Inc., Series C N/A 000000000 3420640.00000000 NS USD 4925721.60000000 0.046432067553 Long EP CORP US Y 3 N N N ANTHEM INC 8MYN82XMYQH89CTMTH67 036752103 390382.00000000 NS USD 158584879.86000000 1.494892414265 Long EC CORP US N 1 N N N SANOFI 549300E9PC51EN656011 80105N105 1008695.00000000 NS USD 47983621.15000000 0.452315197574 Long EC CORP FR N 1 N N N MedTech Acquisition Corp/NY N/A 58507N105 831621.00000000 NS USD 8291261.37000000 0.078157159356 Long EC CORP US N 1 N N INTUITIVE SURGICAL INC 54930052SRG011710797 46120E602 720929.00000000 NS USD 233826111.86000000 2.204150113083 Long EC CORP US N 1 N N N AMEDISYS INC 5299001RBS9GK9STN379 023436108 364528.00000000 NS USD 50906335.20000000 0.479866014942 Long EC CORP US N 1 N N N ILLUMINA INC SQ95QG8SR5Q56LSNF682 452327109 206314.00000000 NS USD 75372693.62000000 0.710496915183 Long EC CORP US N 1 N N N BLACKROCK LIQUIDITY FUNDS T-FUND PORTFOLIO 5493002L9DNZ83RX7V61 09248U718 88050181.10000000 NS USD 88050181.10000000 0.830000614921 Long STIV RF US N 1 N N N McKesson Corp 549300WZWOM80UCFSF54 58155Q103 114383.00000000 NS USD 24793659.08000000 0.233716183493 Long EC CORP US N 1 N N N Design Therapeutics Inc N/A 25056L103 257492.00000000 NS USD 4310416.08000000 0.040631920937 Long EC CORP US N 1 N N Avantor Inc N/A 05352A100 2619447.00000000 NS USD 103415767.56000000 0.974843544840 Long EC CORP US N 1 N N N Genmab A/S 529900MTJPDPE4MHJ122 372303206 373665.00000000 NS USD 14393575.80000000 0.135680320195 Long EC CORP DK N 1 N N Krystal Biotech Inc 549300YONUY68210OE41 501147102 67932.00000000 NS USD 5471922.60000000 0.051580803878 Long EC CORP US N 1 N N N CareMax Inc N/A 14171W103 426569.00000000 NS USD 2858012.30000000 0.026940909567 Long EC CORP US N 1 N N N Henry Schein Inc VGO3WGL8H45T73F4RR92 806407102 748788.00000000 NS USD 53208875.28000000 0.501570793494 Long EC CORP US N 1 N N AMGEN INC 62QBXGPJ34PQ72Z12S66 031162100 1166607.00000000 NS USD 232014800.16000000 2.187075874211 Long EC CORP US N 1 N N N CENTENE CORP 549300Z7JJ4TQSQGT333 15135B101 1055719.00000000 NS USD 75388893.79000000 0.710649625273 Long EC CORP US N 1 N N Helix Acquisition Corp N/A 000000000 226542.00000000 NS USD 2249562.06000000 0.021205383904 Long EC CORP US N 1 N N N Dexcom Inc 549300YSK3QDSFR5EU59 252131107 70130.00000000 NS USD 39454436.70000000 0.371915268240 Long EC CORP US N 1 N N N BIOMARIN PHARMACEUTICAL INC NSLL8ITTRR0J5HEMR848 09061G101 293086.00000000 NS USD 25290390.94000000 0.238398601451 Long EC CORP US N 1 N N N Exact Sciences Corp 549300VM3X1FYD4N9Z14 30063P105 261921.00000000 NS USD 22360195.77000000 0.210777263680 Long EC CORP US N 1 N N N CAREMAX INC N/A 14171W111 88432.00000000 NC USD 123804.80000000 0.001167039736 N/A DE CORP US N 1 CAREMAX INC N/A Call Purchased CareMax Inc CareMax Inc 1.00000000 0.00000000 USD 2025-07-16 XXXX -15289.89000000 N N N Decibel Therapeutics Inc N/A 24343R106 473273.00000000 NS USD 3265583.70000000 0.030782860923 Long EC CORP US N 1 N N Encompass Health Corp 549300FVRPM9DRQZRG64 29261A100 743266.00000000 NS USD 42826986.92000000 0.403706443698 Long EC CORP US N 1 N N N Carbon Health Technologies Inc. N/A 000000000 16855.00000000 NS USD 16953711.27000000 0.159813308769 Long EP CORP US Y 3 N N N ABIOMED Inc 5493001EZN4ZTB4Z5887 003654100 278138.00000000 NS USD 87552279.64000000 0.825307171787 Long EC CORP US N 1 N N Novavax Inc 529900J4GJHPEPQ23205 670002401 170560.00000000 NS USD 35583932.80000000 0.335430157398 Long EC CORP US N 1 N N Novocure Ltd 213800YPP55UMHWA4826 000000000 163820.00000000 NS USD 15340104.80000000 0.144602728329 Long EC CORP JE N 1 N N Seagen Inc N/A 81181C104 1155385.00000000 NS USD 184861600.00000000 1.742588598439 Long EC CORP US N 1 N N N Acerta Pharma BV, Series B N/A 000000000 297971595.00000000 NS USD 42678471.55000000 0.402306471013 Long EC CORP US Y 3 N N N Ideaya Biosciences Inc 549300ULW08F62IJML11 45166A102 187839.00000000 NS USD 4132458.00000000 0.038954408023 Long EC CORP US N 1 N N N Nautilus Biotechnology Inc N/A 63909J108 308716.00000000 NS USD 1497272.60000000 0.014113965050 Long EC CORP US N 1 N N N Forma Therapeutics Holdings In N/A 34633R104 222122.00000000 NS USD 3218547.78000000 0.030339479183 Long EC CORP US N 1 N N AbbVie Inc FR5LCKFTG8054YNNRU85 00287Y109 1051581.00000000 NS USD 121226257.68000000 1.142733236457 Long EC CORP US N 1 N N N Medtronic PLC 549300GX3ZBSQWUXY261 000000000 1617742.00000000 NS USD 172613071.40000000 1.627128458064 Long EC CORP IE N 1 N N N Prothena Corp PLC 5299009ZXQ8NIIJ8OL30 000000000 391632.00000000 NS USD 19640344.80000000 0.185138724959 Long EC CORP IE N 1 N N N Health Assurance Acquisition C N/A 42226W109 1747926.00000000 NS USD 17164633.32000000 0.161801554892 Long EC CORP US N 1 N N N LHC Group Inc 5299009NPLWAMRQYZX73 50187A107 368131.00000000 NS USD 42231988.32000000 0.398097719244 Long EC CORP US N 1 N N Cellarity, Inc. series B N/A 000000000 858333.00000000 NS USD 4636030.77000000 0.043701311477 Long EC CORP US Y 3 N N N Imago Biosciences, Inc. N/A 000000000 453401.19047800 NS USD 10021437.19000000 0.094466574925 Long EC CORP US Y 2 N N N TELADOC INC 549300I2PVFBC9MFAC61 87918A105 408665.00000000 NS USD 41377331.25000000 0.390041337249 Long EC CORP US N 1 N N N Kodiak Sciences Inc 254900IXI5NI8C9OQE24 50015M109 91055.00000000 NS USD 8362491.20000000 0.078828603775 Long EC CORP US N 1 N N ZOETIS INC 549300HD9Q1LOC9KLJ48 98978V103 994263.00000000 NS USD 220766156.52000000 2.081041099250 Long EC CORP US N 1 N N N AmerisourceBergen Corp AI8GXW8LG5WK7E9UD086 03073E105 456585.00000000 NS USD 52849713.75000000 0.498185175350 Long EC CORP US N 1 N N N Mersana Therapeutics Inc 529900VWD5VDZ7PVOS22 59045L106 1050918.00000000 NS USD 7083187.32000000 0.066769309929 Long EC CORP US N 1 N N N UNITEDHEALTH GROUP INC 549300GHBMY8T5GXDE41 91324P102 1862949.00000000 NS USD 827559204.78000000 7.800945327659 Long EC CORP US N 1 N N N MONEY MARKET SERIES LLC N/A 000000000 132454943.59100000 NS USD 132481434.58000000 1.248829596866 Long STIV RF US N N/A N N MERCK & CO INC 4YV9Y5M8S0BRK1RP0397 58933Y105 3198663.00000000 NS USD 239611845.33000000 2.258689039385 Long EC CORP US N 1 N N N Hua Medicine N/A 000000000 12850870.00000000 NS 6756177.63000000 0.063686769491 Long EC CORP CN N 2 N N BOSTON SCIENTIFIC CORP Y6ZDD9FP4P8JSSJMW954 101137107 4441788.00000000 NS USD 169098869.16000000 1.594002006946 Long EC CORP US N 1 N N N Insitro, Series C N/A 000000000 592636.00000000 NS USD 10839964.34000000 0.102182380042 Long EC CORP US Y 3 N N N Goldfinch Bio, Inc. SERIES B N/A 000000000 2345865.00000000 NS USD 3026165.85000000 0.028526000571 Long EC CORP US Y 3 N N N Annexon Inc N/A 03589W102 141165.00045000 NS USD 2299577.86000000 0.021676855334 Long EC CORP US N 1 N N Talaris Therapeutics Inc N/A 87410C104 451718.00000000 NS USD 5854265.28000000 0.055184937970 Long EC CORP US N 1 N N NEVRO CORP 254900SH91I4BOYKUE38 64157F103 432195.00000000 NS USD 37635540.60000000 0.354769535402 Long EC CORP US N 1 N N NUVATION BIO INC N/A 67080N119 77354.00000000 NC USD 162443.40000000 0.001531264560 N/A DE CORP US N 1 NUVATION BIO INC N/A Call Purchased Nuvation Bio Inc Nuvation Bio Inc 1.00000000 11.50000000 USD 2027-07-07 XXXX -4696.94000000 N N N ARENA PHARMACEUTICALS INC 529900CVGQMPJ3A3NI85 040047607 278584.00000000 NS USD 15180042.16000000 0.143093905883 Long EC CORP US N 1 N N N IsoPlexis Corp N/A 465005106 554988.00000000 NS USD 6709804.92000000 0.063249639467 Long EC CORP US N 1 N N N Wuxi Biologics Cayman Inc 5493001TD2TH6VDTJU11 000000000 2097000.00000000 NS 28288092.74000000 0.266656287083 Long EC CORP CN N 2 N N N Zimmer Biomet Holdings Inc 2P2YLDVPES3BXQ1FRB91 98956P102 1137446.00000000 NS USD 136038541.60000000 1.282360487740 Long EC CORP US N 1 N N N Neurocrine Biosciences Inc 549300FECER0XBN49756 64125C109 345389.00000000 NS USD 28753634.25000000 0.271044690772 Long EC CORP US N 1 N N N Quest Diagnostics Inc 8MCWUBXQ0WE04KMXBX50 74834L100 622705.00000000 NS USD 92583779.40000000 0.872736351859 Long EC CORP US N 1 N N N Global Blood Therapeutics Inc 549300U4G0QKK99GRT15 37890U108 457376.00000000 NS USD 12925445.76000000 0.121841066025 Long EC CORP US N 1 N N N Sigilon Therapeutics Inc N/A 82657L107 332626.00000000 NS USD 1250673.76000000 0.011789413456 Long EC CORP US N 1 N N N Immuneering Corp N/A 45254E107 264380.00000000 NS USD 5982919.40000000 0.056397689578 Long EC CORP US N 1 N N Biogen Inc W8J5WZB5IY3K0NDQT671 09062X103 662979.00000000 NS USD 156290669.46000000 1.473266155023 Long EC CORP US N 1 N N N Affinivax Inc., Series C N/A 000000000 122824.00000000 NS USD 4266905.76000000 0.040221773088 Long EC CORP US Y 3 N N N Daiichi Sankyo Co Ltd 353800XGIU2IHQGC9504 000000000 2246300.00000000 NS 55834301.80000000 0.526319244875 Long EC CORP JP N 2 N N N Hansoh Pharmaceutical Group Co 254900Q6MR00EBXTPF42 000000000 16248176.00000000 NS 33305199.87000000 0.313949795751 Long EC CORP CN N 2 N N N Cano Health, Inc. N/A 000000000 2900000.00000000 NS USD 27086000.00000000 0.255324820175 Long EC CORP US Y 2 N N N BioNTech SE 894500UZJ5LG1F8J1U58 09075V102 306430.00000000 NS USD 107783688.20000000 1.016017529628 Long EC CORP DE N 1 N N N DENTSPLY SIRONA Inc 9NHEHR1SOZCYXDO8HO28 24906P109 953620.00000000 NS USD 46479438.80000000 0.438136098112 Long EC CORP US N 1 N N N Omega Therapeutics Inc N/A 68217N105 370072.00000000 NS USD 6694602.48000000 0.063106334429 Long EC CORP US N 1 N N N 2022-01-25 BlackRock Funds Ann Frechette Ann Frechette Assistant Treasurer