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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 BZSXY4R8TzrPXgpzjrBubORu2e8jtHdfnwKJWBoahNQerBcbHRWOXjmGMzdI1ejI
 dlP4Y3mg+Q34/5aP/gH0pg==

<SEC-DOCUMENT>0001181431-05-029675.txt : 20050520
<SEC-HEADER>0001181431-05-029675.hdr.sgml : 20050520
<ACCEPTANCE-DATETIME>20050520192611
ACCESSION NUMBER:		0001181431-05-029675
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050510
FILED AS OF DATE:		20050520
DATE AS OF CHANGE:		20050520

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			APHTON CORP
		CENTRAL INDEX KEY:			0000840319
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				953640931
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		PO BOX 1049
		STREET 2:		STE 51-507
		CITY:			WOODLAND
		STATE:			CA
		ZIP:			95776
		BUSINESS PHONE:		5306616077

	MAIL ADDRESS:	
		STREET 1:		PO BOX 1049
		STREET 2:		STE 51-507
		CITY:			WOODLAND
		STATE:			CA
		ZIP:			95776

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ruediger Manfred
		CENTRAL INDEX KEY:			0001327351

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-19122
		FILM NUMBER:		05849512

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		215-218-4340

	MAIL ADDRESS:	
		STREET 1:		8 PENN CENTER, SUITE 2300
		STREET 2:		1628 JFK BOULEVARD
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19103
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>rrd78854.xml
<DESCRIPTION>FORM 3
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2005-05-10</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000840319</issuerCik>
        <issuerName>APHTON CORP</issuerName>
        <issuerTradingSymbol>APHT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001327351</rptOwnerCik>
            <rptOwnerName>Ruediger Manfred</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>8 PENN CENTER, SUITE 2300</rptOwnerStreet1>
            <rptOwnerStreet2>1628 JFK BOULEVARD</rptOwnerStreet2>
            <rptOwnerCity>PHILADELPHIA</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chief Operating Officer</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>353157</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See footnote.</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">These shares are held by a trust of which Mr. Ruediger is the beneficiary.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Manfred Ruediger</signatureName>
        <signatureDate>2005-05-20</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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