-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 OI5aoSi5q9JoYOqQfWd85QdGWbmTKsFUkc1yHHkRxE2XOJIuWQpgPiXhYfrYRMqm
 FxX60Org8N9nfmSNjFKCMw==

<SEC-DOCUMENT>0001181431-05-017810.txt : 20050318
<SEC-HEADER>0001181431-05-017810.hdr.sgml : 20050318
<ACCEPTANCE-DATETIME>20050318155414
ACCESSION NUMBER:		0001181431-05-017810
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050317
FILED AS OF DATE:		20050318
DATE AS OF CHANGE:		20050318

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			APHTON CORP
		CENTRAL INDEX KEY:			0000840319
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				953640931
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		PO BOX 1049
		STREET 2:		STE 51-507
		CITY:			WOODLAND
		STATE:			CA
		ZIP:			95776
		BUSINESS PHONE:		5306616077

	MAIL ADDRESS:	
		STREET 1:		PO BOX 1049
		STREET 2:		STE 51-507
		CITY:			WOODLAND
		STATE:			CA
		ZIP:			95776

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SMITH JAMES FRANCIS
		CENTRAL INDEX KEY:			0001278350

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-19122
		FILM NUMBER:		05691721

	MAIL ADDRESS:	
		STREET 1:		80 SW 8TH ST
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33130
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd50998.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-03-17</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000840319</issuerCik>
        <issuerName>APHTON CORP</issuerName>
        <issuerTradingSymbol>APHT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001278350</rptOwnerCik>
            <rptOwnerName>SMITH JAMES FRANCIS</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>8 PENN CENTER, SUITE 2300</rptOwnerStreet1>
            <rptOwnerStreet2>1628 JFK BOULEVARD</rptOwnerStreet2>
            <rptOwnerCity>PHILADELPHIA</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19103</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Senior VP and CFO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2005-03-17</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>15000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>1.24</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>15000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ James F. Smith</signatureName>
        <signatureDate>2005-03-18</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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