Stock Plans and Share-Based Compensation - Share-Based Compensation Related to Employees and Directors (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total cost of share-based compensation included in income, before income tax	$ 38,685	$ 10,927	$ 12,896
Income tax benefit	8,898	2,513	2,966
Total cost of employee share-based compensation, after tax	29,787	8,414	9,930
Cost of products
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total cost of share-based compensation included in income, before income tax	1,219	763	961
Selling, general and administrative expenses
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total cost of share-based compensation included in income, before income tax	36,524	9,326	10,955
Research and development expenses
Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Line Items]
Total cost of share-based compensation included in income, before income tax	$ 942	$ 838	$ 980