Exhibit 99-B.10 – Consent of Ernst & Young LLP, Independent Registered Public
Accounting Firm

We consent to the reference to our firm under the caption “Independent Registered Public
Accounting Firm” and to the use of our report dated March 23, 2007, with respect to the
financial statements of ING USA Annuity and Life Insurance Company as of December
31, 2006 and 2005, and for each of the three years in the period ended December 31,
2006, and to the use of our report dated March 23, 2007, with respect to the statements of
assets and liabilities of Separate Account B of ING USA Annuity and Life Insurance
Company as of December 31, 2006, and the related statements of operations and changes
in net assets for the periods disclosed in the financial statements, incorporated by
reference in Post-Effective Amendment No. 5 to the Registration Statement (Form N-4
333-133944), and the related Prospectus and Statement of Additional Information of
Separate Account B of ING USA Annuity and Life Insurance Company.

/s/ Ernst & Young LLP

Atlanta, Georgia
December 10, 2007