<SEC-DOCUMENT>0001133228-22-003485-index.html : 20220507
<SEC-HEADER>0001133228-22-003485.hdr.sgml : 20220506
<ACCEPTANCE-DATETIME>20220505170620
ACCESSION NUMBER:		0001133228-22-003485
CONFORMED SUBMISSION TYPE:	497K
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20220505
DATE AS OF CHANGE:		20220505
EFFECTIVENESS DATE:		20220505

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			MORGAN STANLEY INSTITUTIONAL FUND INC
		CENTRAL INDEX KEY:			0000836487
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			MD
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		497K
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	033-23166
		FILM NUMBER:		22897567

	BUSINESS ADDRESS:	
		STREET 1:		522 FIFTH AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10036
		BUSINESS PHONE:		800-548-7786

	MAIL ADDRESS:	
		STREET 1:		522 FIFTH AVENUE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10036

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MORGAN STANLEY DEAN WITTER INSTITUTIONAL FUND INC
		DATE OF NAME CHANGE:	19990329

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	MORGAN STANLEY INSTITUTIONAL FUND INC
		DATE OF NAME CHANGE:	19920703
<SERIES-AND-CLASSES-CONTRACTS-DATA>
<EXISTING-SERIES-AND-CLASSES-CONTRACTS>
<SERIES>
<OWNER-CIK>0000836487
<SERIES-ID>S000041864
<SERIES-NAME>Global Sustain Portfolio
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000129960
<CLASS-CONTRACT-NAME>Class I
<CLASS-CONTRACT-TICKER-SYMBOL>MGQIX
</CLASS-CONTRACT>
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000129961
<CLASS-CONTRACT-NAME>Class A
<CLASS-CONTRACT-TICKER-SYMBOL>MGQAX
</CLASS-CONTRACT>
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000129962
<CLASS-CONTRACT-NAME>Class L
<CLASS-CONTRACT-TICKER-SYMBOL>MGQLX
</CLASS-CONTRACT>
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000129963
<CLASS-CONTRACT-NAME>Class IS
<CLASS-CONTRACT-TICKER-SYMBOL>MGQSX
</CLASS-CONTRACT>
<CLASS-CONTRACT>
<CLASS-CONTRACT-ID>C000155911
<CLASS-CONTRACT-NAME>Class C
<CLASS-CONTRACT-TICKER-SYMBOL>MSGQX
</CLASS-CONTRACT>
</SERIES>
</EXISTING-SERIES-AND-CLASSES-CONTRACTS>
</SERIES-AND-CLASSES-CONTRACTS-DATA>
</SEC-HEADER>
<DOCUMENT>
<TYPE>497K
<SEQUENCE>1
<FILENAME>msifgsp-html5020_497k.htm
<DESCRIPTION>MSIF GLOBAL SUSTAIN PORTFOLIO_497K
<TEXT>
Document 1 - file: msifgsp-html5020_497k.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>2
<FILENAME>sp15399img002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: sp15399img002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>sp15399img003.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: sp15399img003.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>sp15399img001.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: sp15399img001.jpg

</DOCUMENT>
</SEC-DOCUMENT>