Accounts Payable and Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Accounts payable and accrued expenses [Abstract]
Accrued consulting and clinical trial costs	$ 2,960	$ 2,662
Accrued payroll and related costs	1,845	1,722
Legal and professional fees	3,605	1,063
Accounts payable and other	452	1,040
Other	682	83
Total	$ 9,544	$ 6,570