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Fair Value Measurements (Details) (USD $)
In Thousands, unless otherwise specified
9 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 9 Months Ended 12 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2014
Dec. 31, 2013
Sep. 30, 2013
Sep. 30, 2014
Auction Rate Securities [Member]
Sep. 30, 2013
Auction Rate Securities [Member]
Sep. 30, 2014
Auction Rate Securities [Member]
Sep. 30, 2013
Auction Rate Securities [Member]
Dec. 31, 2013
Auction Rate Securities [Member]
Sep. 30, 2014
Auction Rate Securities [Member]
Minimum [Member]
Dec. 31, 2013
Auction Rate Securities [Member]
Minimum [Member]
Sep. 30, 2014
Auction Rate Securities [Member]
Maximum [Member]
Dec. 31, 2013
Auction Rate Securities [Member]
Maximum [Member]
Sep. 30, 2014
Auction Rate Securities [Member]
Weighted average [Member]
Dec. 31, 2013
Auction Rate Securities [Member]
Weighted average [Member]
Sep. 30, 2014
Azedra commercialization [Member]
Dec. 31, 2013
Azedra commercialization [Member]
Sep. 30, 2014
MIP - 1404 commercialization [Member]
Dec. 31, 2013
MIP - 1404 commercialization [Member]
Jun. 30, 2014
MIP-1095 commercialization [Member]
Sep. 30, 2014
MIP-1095 commercialization [Member]
Dec. 31, 2013
MIP-1095 commercialization [Member]
Sep. 30, 2014
Net sales targets [Member]
Dec. 31, 2013
Net sales targets [Member]
Sep. 30, 2014
Net sales targets [Member]
Minimum [Member]
Dec. 31, 2013
Net sales targets [Member]
Minimum [Member]
Sep. 30, 2014
Net sales targets [Member]
Maximum [Member]
Dec. 31, 2013
Net sales targets [Member]
Maximum [Member]
Sep. 30, 2014
Net sales targets [Member]
Weighted average [Member]
Dec. 31, 2013
Net sales targets [Member]
Weighted average [Member]
Sep. 30, 2014
Contingent Consideration Liability [Member]
Sep. 30, 2013
Contingent Consideration Liability [Member]
Sep. 30, 2014
Contingent Consideration Liability [Member]
Sep. 30, 2013
Contingent Consideration Liability [Member]
Sep. 30, 2014
U.S. Government Subsidized Securities [Member]
Sep. 30, 2014
Recurring [Member]
Dec. 31, 2013
Recurring [Member]
Sep. 30, 2014
Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Dec. 31, 2013
Recurring [Member]
Quoted Prices in Active Markets for Identical Assets (Level 1) [Member]
Sep. 30, 2014
Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Dec. 31, 2013
Recurring [Member]
Significant Other Observable Inputs (Level 2) [Member]
Sep. 30, 2014
Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Dec. 31, 2013
Recurring [Member]
Significant Unobservable Inputs (Level 3) [Member]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]                                                                                    
Contingent consideration liability $ 17,100 $ 15,700 $ 15,900                                                               $ 17,100 $ 15,700 $ 0 $ 0 $ 0 $ 0 $ 17,100 $ 15,700
Money Market Funds                                                                     70,397 60,364 70,397 60,364 0 0 0 0
Auction Rate Securities 2,208 2,208                                                               2,208 2,208 2,208 0 0 0 0 2,208 2,208
Asset, total                                                                     72,605 62,572 70,397 60,364 0 0 2,208 2,208
Liability, total                                                                     17,100 15,700 0 0 0 0 17,100 15,700
Maturity period of US government subsidized securities (in years) 10 years                                                                                  
Duration of securities subject to temporary impairment, minimum (in months) 12 months                                                                                  
Amount of temporary impairment 192 192                                                                                
Summary of activities in financial instruments with significant Level 3 inputs [Roll Forward]                                                                                    
Balance at beginning of period       2,208 2,208 2,208 3,240 3,240                                           16,600 15,900 15,700 0                  
Transfers into Level 3       0 0 0 0                                                                      
Total realized/unrealized gains (losses)                                                                                    
Included in net income (loss)       0 0 0 0                                                                      
Included in other comprehensive incomet (loss)       0 0 0 68                                                                      
Settlements       0 0 0 (1,100)                                                                      
Fair value of contingent consideration - acquisition of Molecular Insight                                                               0 15,900                  
Fair value change to contingent consideration included in net loss                                                           500 0 1,400 0                  
Balance at end of period       2,208 2,208 2,208 2,208 2,208                                           17,100 15,900 17,100 15,900                  
Changes in unrealized gains or losses for the period included in earnings (or changes in net assets) for liabilities held at the end of the reporting period                                                           500 0 1,400 0                  
Total amount of unrealized gains (losses) for the period included in other comprehensive loss attributable to the change in fair market value of related assets still held at the reporting date       0 0 0 0                                                                      
Fair Value Measurements, Quantitative Information                                                                                    
Period of milestone expected achievement                             2017 2017 2018 2018   2021 2021     2018 2018 2022 2022                              
Fair Value       $ 2,208   $ 2,208   $ 2,208             $ 2,400 $ 2,300 $ 2,200 $ 2,000   $ 500 $ 500 $ 12,000 $ 10,900                                      
Valuation technique           Discounted cash flow model   Discounted cash flow model             Probability adjusted discounted cash flow model Probability adjusted discounted cash flow model Probability adjusted discounted cash flow model Probability adjusted discounted cash flow model   Probability adjusted discounted cash flow model Probability adjusted discounted cash flow model Monte-Carlo simulation Monte-Carlo simulation                                      
Redemption period                 5 years 5 years 15 years 15 years 6 years 6 years                                                        
Discount Rate                 0.25% 0.25% 3.00% 3.00% 1.55% 1.55% 10.00% 10.00% 10.00% 10.00% 10.00%   10.00% 12.50% 12.50%                                      
Probability of success                             40.00% 40.00% 31.00% 31.00%   19.00% 19.00%     19.00% 19.00% 40.00% 40.00% 32.80% 32.80%