CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) (USD $) In Thousands, except Per Share data, unless otherwise specified	3 Months Ended
	Mar. 31, 2014	Mar. 31, 2013
Revenues:
Royalty income	$ 735	$ 1,157
Collaboration revenue	1,049	853
Research grants	0	198
Other revenues	31	18
Total revenues	1,815	2,226
Expenses:
Research and development	6,934	8,721
License fees - research and development	90	70
Royalty expense	82	116
General and administrative	3,890	4,314
Depreciation and amortization	144	277
Total expenses	11,140	13,498
Operating loss	(9,325)	(11,272)
Other income:
Interest income	12	14
Total other income	12	14
Net loss	$ (9,313)	$ (11,258)
Net loss per share - basic and diluted	$ (0.15)	$ (0.22)
Weighted-average shares - basic and diluted	63,958	50,116