Income Taxes (Details) (USD $)	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2011	Jan. 18, 2013
Income Taxes [Abstract]
Income tax provision (benefit)	$ (362,000)	$ 0	$ 0
Deferred tax assets and liabilities [Abstract]
Depreciation and amortization	6,165,000	6,497,000
R&E tax credit carry-forwards	5,129,000	11,843,000
NYS investment tax credit carry-forwards	1,095,000	1,084,000
AMT credit carry-forwards	211,000	211,000
Net operating loss carry-forwards	190,263,000	112,966,000
Capitalized research and development expenditures	25,231,000	30,884,000
Stock compensation	13,826,000	14,436,000
Other items	1,097,000	2,193,000
Total gross deferred tax assets	243,017,000	180,114,000
Less: Valuation allowance	(243,017,000)	(178,045,000)
Deferred tax assets	0	2,069,000
Deferred tax liability - current	0	(2,069,000)
Deferred tax liability - long term	(12,321,000)	0		(12,683,000)
Net deferred tax asset (liability)	(12,321,000)	0
Deferred tax assets, net, current		17,000
Deferred tax assets, net, noncurrent	0	2,052,000
Reconciliation of income taxes computed at the Federal statutory income tax rate to the actual effective income tax [Abstract]
U.S. Federal statutory rate (in hundredths)	(34.00%)	(35.00%)	35.00%
State income taxes, net of Federal benefit (in hundredths)	(4.90%)	(5.40%)	8.00%
Research and experimental tax credit (in hundredths)	(3.60%)	0.00%	(4.10%)
Change in valuation allowance (in hundredths)	11.40%	34.70%	(22.60%)
Effect of federal tax rate bracket change on valuation allowance (in hundredths)	8.70%	0.00%	(34.80%)
Equity compensation (in hundredths)	3.10%	4.20%	17.00%
Investment tax credit (in hundredths)	(0.10%)	0.00%	(0.10%)
NOL expiration - Section 382	18.60%	0.00%	0.00%
Other (in hundredths)	0.00%	1.50%	1.60%
Income tax provision (benefit) (in hundredths)	(0.80%)	0.00%	0.00%
Net operating loss carryforwards - federal	513,800,000
Net operating loss carryforwards - state	453,100,000
Unrecognized tax benefit amount that would affect effective tax rate	0
Net operating loss carry-forwards not reflected in deferred tax assets	18,200,000
Valuation allowance related to net operating loss carryforwards attributable to excess tax deductions for equity compensation	11,200,000
Unrecognized tax benefits	(362,000)	0	0
Tax credit carryforwards of R&E expired	20,000
Deferred tax assets	0	2,069,000
Deferred Tax Liabilities, Net, Current	0	2,069,000
Deferred tax liability - long term	12,321,000	0		12,683,000
Tax Credit Carryforward, Amount	5,100,000
Income Taxes [Abstract]
Unrecognized tax benefits	2,661,000	2,661,000
Current year - increases	0
Current year - decreases	0
Settlements	0
Expired statuses	$ 0