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Commitments and Contingencies (Details) (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Future minimum annual payments under operating lease agreements [Abstract]      
2014 $ 1,841    
2015 1,887    
2016 1,934    
2017 1,983    
2018 2,032    
Thereafter 4,218    
Total 13,895    
Rental expense 3,548 2,074 3,475
Adjustments to rental expense (164) (419) 63
Additional facility charges 2,330 2,845 4,033
Licensing, Service, Supply and Related Party Agreements [Abstract]      
License fees and supply costs 567 1,170 578
Consulting Agreements [Abstract]      
Expenses with regard to consulting agreements with scientific specialists 39 8 27
Fair value of options vested included in consulting expenses 7   11
Retirement Agreement [Abstract]      
Expenses for termination of employment agreement   1,789  
MTS-Related Party Agreement      
Consulting agreement monthly retainer amount 55    
Success fee 300    
Parent Company [Member] | Lonza Sales AG [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 909    
Future Commitments 824    
Terms Annual license fee payments, milestones and royalties, as applicable, in respect of oncology and other products.    
PSMA Development Company LLC [Member] | Seattle Genetics, Inc. [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 4,400    
Future Commitments 13,900    
PSMA Development Company LLC [Member] | Amgen Fremont, Inc. (formerly Abgenix) [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 1,350    
Future Commitments 5,750    
PSMA Development Company LLC [Member] | Former Member of PSMA LLC [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 278    
Future Commitments 52,188    
Terms Annual minimum royalty payments and milestones to use technology related to PSMA.    
MIP [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 216    
Future Commitments 3,453    
MIP [Member] | Seattle Genetics, Inc. [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Terms Milestone and periodic maintenance payments to use ADC technology to link chemotherapeutic agents to monoclonal antibodies that target prostate specific membrane antigen. ADC technology is based in part on technology licensed by SGI from third parties.    
MIP [Member] | Amgen Fremont, Inc. (formerly Abgenix) [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Terms Milestones and royalties to use XenoMouse® technology for generating fully human antibodies to PSMA LLC’s PSMA antigen.    
MIP [Member] | Former Member of PSMA LLC [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Terms Payments for programs to be out-licensed or terminated    
MIP [Member] | University of Zurich and the Paul Scherrer Institute [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 65    
Future Commitments 1,225    
Terms Annual maintenance and license fee payments, milestones and royalties in respect of licensed technology related to 1404.    
MIP [Member] | University of Western Ontario [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 4    
Future Commitments 374    
Terms Annual minimum royalty, administration and milestone payments in respect of licensed technology related to Azedra.    
MIP [Member] | Novartis Pharma AG and other interests [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 0    
Future Commitments 4,600    
Terms Milestone and royalty payments in respect of licensed technology related to Onalta.    
MIP [Member] | Bayer Schering Pharma AG [Member]
     
Licensing, Service, Supply and Related Party Agreements [Abstract]      
Commitments, paid from inception 0    
Future Commitments $ 9,000    
Terms Milestone and royalty payments in respect of licensed technology related to a MIP asset.