STATEMENTS OF OPERATIONS (Unaudited) (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Revenues:
Collaboration revenue	$ 72,460	$ 880	$ 73,543	$ 1,093
Royalty income	527	581	527	1,206
Research grants	1,401	789	2,665	1,433
Other revenues	19	55	60	96
Total revenues	74,407	2,305	76,795	3,828
Expenses:
Research and development	13,302	10,659	32,481	22,551
License fees - research and development	88	291	452	1,107
General and administrative	4,952	5,680	10,149	12,154
Royalty expense	70	58	127	120
Depreciation and amortization	525	874	1,061	1,751
Total expenses	18,937	17,562	44,270	37,683
Operating income (loss)	55,470	(15,257)	32,525	(33,855)
Other income:
Interest income	16	16	34	31
Total other income	16	16	34	31
Net income (loss)	$ 55,486	$ (15,241)	$ 32,559	$ (33,824)
Net income (loss) per share - basic	$ 1.66	$ (0.47)	$ 0.97	$ (1.05)
Weighted-average shares - basic	33,510	32,396	33,397	32,251
Net income (loss) per share - diluted	$ 1.64	$ (0.47)	$ 0.97	$ (1.05)
Weighted-average shares - diluted	33,787	32,396	33,567	32,251