Note 2 - Liquidity and Basis of Presentation (Details Textual) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2018	Jun. 30, 2017	Jun. 30, 2018	Jun. 30, 2017	Dec. 31, 2017
Net Income (Loss) Attributable to Parent, Total	$ (319,039)	$ (1,875,446)	$ (12,395,021)	$ (4,603,886)
Net Cash Provided by (Used in) Operating Activities, Total			(1,125,686)	$ (483,308)
Assets, Current, Total	536,694		536,694		$ 280,839
Liabilities, Current, Total	1,202,880		1,202,880		1,233,077
Accrued Bonuses, Current	63,537		63,537
Notes Payable, Current, Total	66,415		66,415		$ 212,134
Accounts Payable to Compounder	159,310		159,310
Current Liabilities [Member]
Disputed Accrued Expenses	156,200		156,200
Financing of D&O and G/L Policies [Member]
Notes Payable, Current, Total	59,810		59,810
Payment in Kind (PIK) Note [Member]
Interest Payable	$ 338,741		$ 338,741