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Note 9 - Options and Warrants to Purchase Common Stock (Tables)
 6 Months Ended
Jun. 30, 2018
Notes Tables  
Schedule of Warrants or Rights [Table Text Block]
   
Shares Issuable
upon exercise of
          
   
upon Exercise of
    
Weighted Average
  
   
Outstanding
Warrants
    
Exercise Price
  
                 
Outstanding at January 1, 2018
    
18,813,373
     $
0.14
  
Issued
    
8,000,000
     $
0.15
  
Exercised
    
(2,000,000
)
   $
0.04
  
Forfeited
    
--
      
--
  
Outstanding at June 30, 2018
    
24,813,373
     $
0.15
  
Schedule of Stockholders' Equity Note, Warrants or Rights [Table Text Block]
 
 
 
 
Warrants Outstanding and Exercisable
 
 
 
 
 
Shares Issuable
 
 
Weighted Average
 
 
 
 
 
 
 
 
 
upon Exercise of
 
 
Remaining
 
 
Weighted Average
 
Exercise Price
 
 
Outstanding Warrants
 
 
Contractual Life (years)
 
 
Exercise Price
 
$
1.15
 
 
 
461,340
 
 
 
2.8
 
 
$
1.15
 
$
0.25
 
 
 
3,283,283
 
 
 
3.0
 
 
$
0.25
 
$
0.04
 
 
 
2,068,750
 
 
 
4.3
 
 
$
0.04
 
$
0.10
 
 
 
11,000,000
 
 
 
4.5
 
 
$
0.10
 
$
0.15
      
8,000,000
      
3.0
    
$
0.15
  
 
 
 
 
 
24,813,373
 
 
 
5.2
 
 
$
0.15
 
Schedule of Share-based Payment Award, Stock Options, Valuation Assumptions [Table Text Block]
Dividend Yield
 
 
0%
 
  
Expected Life (in years)
 
2.48
–
2.96
  
Expected Volatility
 
163.73%
–
177.59%
  
Risk Free Interest Rate
 
2.54%
–
2.62%
  
Share-based Compensation, Stock Options, Activity [Table Text Block]
   
Shares Issuable
    
Weighted
  
   
Upon Exercise of
    
Average
  
   
Options
    
Exercise Price
  
                 
Outstanding at December 31, 2017
    
57,057,768
     $
0.36
  
Granted
    
4,224,999
     $
0.11
  
Exercised
    
--
      
--
  
Forfeited
    
(232,645
)
    
1.36
  
Outstanding at June 30, 2018
    
61,050,122
     $
0.34
  
Schedule of Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Table Text Block]
Options Outstanding
    
Options Exercisable
  
Number Outstanding
    
 
Weighted
Average
Remaining
Contractual
Life (years)
    
Weighted
Average
Exercise
Price
    
Number
Exercisable
    
Weighted
Average
Exercise
Price
  
                                   
35,322,222      
9.34
     $
0.06
      
26,697,225
     $
0.06
  
545,289      
9.48
     $
0.075
      
408,968
     $
0.075
  
377,777      
4.93
     $
0.11
      
69,444
     $
0.11
  
3,000,000      
4.61
     $
0.12
      
1,000,000
     $
0.12
  
500,000      
3.13
     $
0.16
      
500,000
     $
0.16
  
81,395      
5.64
     $
0.21
      
81,395
     $
0.21
  
100,000      
2.22
     $
0.22
      
100,000
     $
0.22
  
1,066,155      
2.87
     $
0.24
      
1,066,155
     $
0.24
  
2,087,500      
4.29
     $
0.25
      
2,087,500
     $
0.25
  
35,595      
4.79
     $
0.27
      
35,595
     $
0.27
  
474,815      
5.86
     $
0.28
      
474,815
     $
0.28
  
234,506      
4.64
     $
0.285
      
234,506
     $
0.285
  
81,522      
2.56
     $
0.30
      
81,522
     $
0.30
  
200,000      
6.63
     $
0.66
      
200,000
     $
0.66
  
150,000      
6.61
     $
0.68
      
150,000
     $
0.68
  
7,233,277      
0.50
     $
0.70
      
7,233,277
     $
0.70
  
488,356      
6.89
     $
0.73
      
488,356
     $
0.73
  
3,104,653      
3.65
     $
0.83
      
3,104,653
     $
0.83
  
975,000      
5.95
     $
0.84
      
975,000
     $
0.84
  
300,000      
5.14
     $
1.10
      
300,000
     $
1.10
  
300,000      
4.99
     $
1.15
      
300,000
     $
1.15
  
115,000      
2.74
     $
1.35
      
115,000
     $
1.35
  
300,000      
3.90
     $
1.55
      
300,000
     $
1.55
  
3,077,060      
4.39
     $
1.66
      
3,077,060
     $
1.66
  
900,000      
3.14
     $
1.90
      
900,000
     $
1.90
  
61,050,122      
6.82
     $
0.34
      
49,980,471
     $
0.40