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Note 9 - Options and Warrants to Purchase Common Stock - Summary of the Status of the Warrants Outstanding (Details) - $ / shares
3 Months Ended
Mar. 31, 2018
Dec. 31, 2017
Warrants Outstanding and Exercisable Shares Issuable upon Exercise of Outstanding Warrants (in shares) 18,313,373  
Warrants Outstanding and Exercisable Weighted Average Remaining Contractual Life (Year) 4 years 146 days  
Warrants Outstanding and Exercisable Weighted Average Exercise Price (in dollars per share) $ 0.14 $ 0.14
Exercise Price 1 [Member]    
Warrants Outstanding and Exercisable Shares Issuable upon Exercise of Outstanding Warrants (in shares) 461,340  
Warrants Outstanding and Exercisable Weighted Average Remaining Contractual Life (Year) 3 years 36 days  
Warrants Outstanding and Exercisable Weighted Average Exercise Price (in dollars per share) $ 1.15  
Exercise Price 2 [Member]    
Warrants Outstanding and Exercisable Shares Issuable upon Exercise of Outstanding Warrants (in shares) 3,283,283  
Warrants Outstanding and Exercisable Weighted Average Remaining Contractual Life (Year) 3 years 73 days  
Warrants Outstanding and Exercisable Weighted Average Exercise Price (in dollars per share) $ 0.25  
Exercise Price 3 [Member]    
Warrants Outstanding and Exercisable Shares Issuable upon Exercise of Outstanding Warrants (in shares) 3,568,750  
Warrants Outstanding and Exercisable Weighted Average Remaining Contractual Life (Year) 4 years 182 days  
Warrants Outstanding and Exercisable Weighted Average Exercise Price (in dollars per share) $ 0.04  
Exercise Price 4 [Member]    
Warrants Outstanding and Exercisable Shares Issuable upon Exercise of Outstanding Warrants (in shares) 11,000,000  
Warrants Outstanding and Exercisable Weighted Average Remaining Contractual Life (Year) 4 years 255 days  
Warrants Outstanding and Exercisable Weighted Average Exercise Price (in dollars per share) $ 0.10