Note 2 - Liquidity and Basis of Presentation (Details Textual) - USD ($)	3 Months Ended
	Mar. 31, 2018	Mar. 31, 2017	Dec. 31, 2017
Net Income (Loss) Attributable to Parent, Total	$ (12,075,982)	$ (2,728,440)
Net Cash Provided by (Used in) Operating Activities, Total	(296,603)	$ (741,557)
Assets, Current, Total	239,639		$ 280,839
Liabilities, Current, Total	1,407,296		1,233,077
Accrued Bonuses, Current	183,149
Notes Payable, Current, Total	118,252		$ 212,134
Accounts Payable to Compounder	158,700
Current Liabilities [Member]
Disputed Accrued Expenses	156,200
Financing of D&O and G/L Policies [Member]
Notes Payable, Current, Total	118,252
Payment in Kind (PIK) Note [Member]
Interest Payable	$ 318,464