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Note 4 - Summary of Significant Accounting Policies - Valuation Assumptions (Details) - Fair Value, Inputs, Level 3 [Member] - $ / shares
9 Months Ended 12 Months Ended
Sep. 30, 2016
Dec. 31, 2015
Series 2023 PIK Note Derivative Liability [Member]    
Market price and estimated fair value of stock (in dollars per share) $ 0.15 $ 0.28
Exercise price (in dollars per share) $ 1.28 $ 1.36
Term (years) 6 years 302 days 7 years 211 days
Expected volatility 89.00% 72.90%
Risk-free interest rate 1.40% 2.12%
Series A PIK Note Derivative Liability [Member]    
Market price and estimated fair value of stock (in dollars per share) $ 0.15 $ 0.28
Exercise price (in dollars per share) $ 0.83 $ 0.92
Term (years) 6 years 302 days 7 years 211 days
Expected volatility 89.00% 72.90%
Risk-free interest rate 1.40% 2.12%